GI involvement in Henoch-Schönlein purpura

Motohiro Esaki, Takayuki Matsumoto, Shotaro Nakamura, Masumi Kawasaki, Keiichiro Iwai, Katsuya Hirakawa, Ken ichi Tarumi, Takashi Yao, Mitsuo Iida

Research output: Contribution to journalArticlepeer-review

102 Citations (Scopus)


Background: The diagnosis of Henoch-Schönlein purpura is difficult, especially when abdominal symptoms precede cutaneous lesions. The aim of this study was to determine the distribution of GI involvement in Henoch-Schönlein purpura. Methods: Endoscopic or radiographic findings throughout the entire GI tract were retrospectively reviewed for 7 patients with Henoch-Schönlein purpura. Histopathologic findings were analyzed and correlated with findings at EGD and colonoscopy. Observations: The duodenum and small intestine were most frequently involved (6 patients, each site). Contrast radiography of the small intestine demonstrated thickened mucosal folds or small barium flecks. Findings at EGD were multiple irregular ulcers, mucosal redness and petechiae in the duodenum. In 4 patients, the second part of the duodenum was predominantly affected. Ulcerating lesions accompanied by hematoma-like protrusions were detected in 4 patients in whom leukocytoclastic vasculitis was proven histopathologically. Conclusions: EGD appears to have the greatest diagnostic utility in patients suspected to have Henoch-Schönlein purpura with GI involvement.

Original languageEnglish
Pages (from-to)920-923
Number of pages4
JournalGastrointestinal endoscopy
Issue number6
Publication statusPublished - Dec 2002

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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