TY - JOUR
T1 - Genes involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide in Streptococcus mutans
AU - Yamashita, Y.
AU - Tsukioka, Y.
AU - Tomihisa, K.
AU - Nakano, Y.
AU - Koga, T.
PY - 1998
Y1 - 1998
N2 - We identified in Streptococcus mutans six new genes (rgpA through rgpF), whose disruption results in a loss of serotype-specific antigenicity, specified by the glucose side chains of rhamnose-glucose polysaccharide from the cell wall. Rhamnose and glucose content of the cell wall decreased drastically in all these disruption mutants, except that in the rgpE mutant only the glucose content decreased. RgpC and RgpD are homologous to ATP- binding cassette transporter components and may be involved in polysaccharide export, whereas RgpE may be a transferase of side chain glucose.
AB - We identified in Streptococcus mutans six new genes (rgpA through rgpF), whose disruption results in a loss of serotype-specific antigenicity, specified by the glucose side chains of rhamnose-glucose polysaccharide from the cell wall. Rhamnose and glucose content of the cell wall decreased drastically in all these disruption mutants, except that in the rgpE mutant only the glucose content decreased. RgpC and RgpD are homologous to ATP- binding cassette transporter components and may be involved in polysaccharide export, whereas RgpE may be a transferase of side chain glucose.
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U2 - 10.1128/jb.180.21.5803-5807.1998
DO - 10.1128/jb.180.21.5803-5807.1998
M3 - Article
C2 - 9791140
AN - SCOPUS:0031795868
SN - 0021-9193
VL - 180
SP - 5803
EP - 5807
JO - Journal of bacteriology
JF - Journal of bacteriology
IS - 21
ER -