Generation of radioisotopes with accelerator neutrons by deuterons

Yasuki Nagai; Kazuyuki Hashimoto; Yuichi Hatsukawa; Hideya Saeki; Shoji Motoishi; Nozomi Sato; Masako Kawabata; Hideo Harada; Tadahiro Kin; Kazuaki Tsukada; Tetsuya K. Sato; Futoshi Minato; Osamu Iwamoto; Nobuyuki Iwamoto; Yohji Seki; Kenji Yokoyama; Takehiko Shiina; Akio Ohta; Nobuhiro Takeuchi; Yukimasa Kawauchi; Norihito Sato; Hisamichi Yamabayashi; Yoshitsugu Adachi; Yuji Kikuchi; Toshinori Mitsumoto; Takashi Igarashi

doi:10.7566/JPSJ.82.064201

Generation of radioisotopes with accelerator neutrons by deuterons

Yasuki Nagai, Kazuyuki Hashimoto, Yuichi Hatsukawa, Hideya Saeki, Shoji Motoishi, Nozomi Sato, Masako Kawabata, Hideo Harada, Tadahiro Kin, Kazuaki Tsukada, Tetsuya K. Sato, Futoshi Minato, Osamu Iwamoto, Nobuyuki Iwamoto, Yohji Seki, Kenji Yokoyama, Takehiko Shiina, Akio Ohta, Nobuhiro Takeuchi, Yukimasa KawauchiNorihito Sato, Hisamichi Yamabayashi, Yoshitsugu Adachi, Yuji Kikuchi, Toshinori Mitsumoto, Takashi Igarashi

Engineering Science for Advanced energy system

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46 Citations (Scopus)

Abstract

A new system proposed for the generation of radioisotopes with accelerator neutrons by deuterons (GRAND) is described by mainly discussing the production of ⁹⁹Mo used for nuclear medicine diagnosis. A prototype facility of this system consists of a cyclotron to produce intense accelerator neutrons from the ^natC(d,n) reaction with 40MeV 2mA deuteron beams, and a sublimation system to separate ^99mTc from an irradiated ¹⁰⁰MoO₃ sample. About 8.1 TBq/week of ⁹⁹Mo is produced by repeating irradiation on an enriched ¹⁰⁰Mo sample (251 g) with accelerator neutrons for two days three times. It meets about 10% of the ⁹⁹Mo demand in Japan. The characteristic feature of the system lies in its capability to reliably produce a wide variety of high-quality, carrier-free, carrier-added radioisotopes with a minimum level of radioactive waste without using uranium. The system is compact in size, and easy to operate; therefore it could be used worldwide to produce radioisotopes for medical, research, and industrial applications.

Original language	English
Article number	064201
Journal	journal of the physical society of japan
Volume	82
Issue number	6
DOIs	https://doi.org/10.7566/JPSJ.82.064201
Publication status	Published - Jun 2013

All Science Journal Classification (ASJC) codes

Physics and Astronomy(all)

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Nagai, Y., Hashimoto, K., Hatsukawa, Y., Saeki, H., Motoishi, S., Sato, N., Kawabata, M., Harada, H., Kin, T., Tsukada, K., Sato, T. K., Minato, F., Iwamoto, O., Iwamoto, N., Seki, Y., Yokoyama, K., Shiina, T., Ohta, A., Takeuchi, N., ... Igarashi, T. (2013). Generation of radioisotopes with accelerator neutrons by deuterons. journal of the physical society of japan, 82(6), Article 064201. https://doi.org/10.7566/JPSJ.82.064201

Nagai, Y, Hashimoto, K, Hatsukawa, Y, Saeki, H, Motoishi, S, Sato, N, Kawabata, M, Harada, H, Kin, T, Tsukada, K, Sato, TK, Minato, F, Iwamoto, O, Iwamoto, N, Seki, Y, Yokoyama, K, Shiina, T, Ohta, A, Takeuchi, N, Kawauchi, Y, Sato, N, Yamabayashi, H, Adachi, Y, Kikuchi, Y, Mitsumoto, T & Igarashi, T 2013, 'Generation of radioisotopes with accelerator neutrons by deuterons', journal of the physical society of japan, vol. 82, no. 6, 064201. https://doi.org/10.7566/JPSJ.82.064201

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abstract = "A new system proposed for the generation of radioisotopes with accelerator neutrons by deuterons (GRAND) is described by mainly discussing the production of 99Mo used for nuclear medicine diagnosis. A prototype facility of this system consists of a cyclotron to produce intense accelerator neutrons from the natC(d,n) reaction with 40MeV 2mA deuteron beams, and a sublimation system to separate 99mTc from an irradiated 100MoO3 sample. About 8.1 TBq/week of 99Mo is produced by repeating irradiation on an enriched 100Mo sample (251 g) with accelerator neutrons for two days three times. It meets about 10% of the 99Mo demand in Japan. The characteristic feature of the system lies in its capability to reliably produce a wide variety of high-quality, carrier-free, carrier-added radioisotopes with a minimum level of radioactive waste without using uranium. The system is compact in size, and easy to operate; therefore it could be used worldwide to produce radioisotopes for medical, research, and industrial applications.",

author = "Yasuki Nagai and Kazuyuki Hashimoto and Yuichi Hatsukawa and Hideya Saeki and Shoji Motoishi and Nozomi Sato and Masako Kawabata and Hideo Harada and Tadahiro Kin and Kazuaki Tsukada and Sato, {Tetsuya K.} and Futoshi Minato and Osamu Iwamoto and Nobuyuki Iwamoto and Yohji Seki and Kenji Yokoyama and Takehiko Shiina and Akio Ohta and Nobuhiro Takeuchi and Yukimasa Kawauchi and Norihito Sato and Hisamichi Yamabayashi and Yoshitsugu Adachi and Yuji Kikuchi and Toshinori Mitsumoto and Takashi Igarashi",

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T1 - Generation of radioisotopes with accelerator neutrons by deuterons

AU - Nagai, Yasuki

AU - Hashimoto, Kazuyuki

AU - Hatsukawa, Yuichi

AU - Saeki, Hideya

AU - Motoishi, Shoji

AU - Sato, Nozomi

AU - Kawabata, Masako

AU - Harada, Hideo

AU - Kin, Tadahiro

AU - Tsukada, Kazuaki

AU - Sato, Tetsuya K.

AU - Minato, Futoshi

AU - Iwamoto, Osamu

AU - Iwamoto, Nobuyuki

AU - Seki, Yohji

AU - Yokoyama, Kenji

AU - Shiina, Takehiko

AU - Ohta, Akio

AU - Takeuchi, Nobuhiro

AU - Kawauchi, Yukimasa

AU - Sato, Norihito

AU - Yamabayashi, Hisamichi

AU - Adachi, Yoshitsugu

AU - Kikuchi, Yuji

AU - Mitsumoto, Toshinori

AU - Igarashi, Takashi

PY - 2013/6

Y1 - 2013/6

N2 - A new system proposed for the generation of radioisotopes with accelerator neutrons by deuterons (GRAND) is described by mainly discussing the production of 99Mo used for nuclear medicine diagnosis. A prototype facility of this system consists of a cyclotron to produce intense accelerator neutrons from the natC(d,n) reaction with 40MeV 2mA deuteron beams, and a sublimation system to separate 99mTc from an irradiated 100MoO3 sample. About 8.1 TBq/week of 99Mo is produced by repeating irradiation on an enriched 100Mo sample (251 g) with accelerator neutrons for two days three times. It meets about 10% of the 99Mo demand in Japan. The characteristic feature of the system lies in its capability to reliably produce a wide variety of high-quality, carrier-free, carrier-added radioisotopes with a minimum level of radioactive waste without using uranium. The system is compact in size, and easy to operate; therefore it could be used worldwide to produce radioisotopes for medical, research, and industrial applications.

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Generation of radioisotopes with accelerator neutrons by deuterons

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