Generation of radioisotopes with accelerator neutrons by deuterons

Yasuki Nagai, Kazuyuki Hashimoto, Yuichi Hatsukawa, Hideya Saeki, Shoji Motoishi, Nozomi Sato, Masako Kawabata, Hideo Harada, Tadahiro Kin, Kazuaki Tsukada, Tetsuya K. Sato, Futoshi Minato, Osamu Iwamoto, Nobuyuki Iwamoto, Yohji Seki, Kenji Yokoyama, Takehiko Shiina, Akio Ohta, Nobuhiro Takeuchi, Yukimasa KawauchiNorihito Sato, Hisamichi Yamabayashi, Yoshitsugu Adachi, Yuji Kikuchi, Toshinori Mitsumoto, Takashi Igarashi

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)


A new system proposed for the generation of radioisotopes with accelerator neutrons by deuterons (GRAND) is described by mainly discussing the production of 99Mo used for nuclear medicine diagnosis. A prototype facility of this system consists of a cyclotron to produce intense accelerator neutrons from the natC(d,n) reaction with 40MeV 2mA deuteron beams, and a sublimation system to separate 99mTc from an irradiated 100MoO3 sample. About 8.1 TBq/week of 99Mo is produced by repeating irradiation on an enriched 100Mo sample (251 g) with accelerator neutrons for two days three times. It meets about 10% of the 99Mo demand in Japan. The characteristic feature of the system lies in its capability to reliably produce a wide variety of high-quality, carrier-free, carrier-added radioisotopes with a minimum level of radioactive waste without using uranium. The system is compact in size, and easy to operate; therefore it could be used worldwide to produce radioisotopes for medical, research, and industrial applications.

Original languageEnglish
Article number064201
Journaljournal of the physical society of japan
Issue number6
Publication statusPublished - Jun 2013

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)


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