Follicular dendritic cell sarcoma of the neck; a case report and literature review

Torahiko Nakashima; Yuichiro Kuratomi; Hideki Shiratsuchi; Hidetaka Yamamoto; Ryuji Yasumatsu; Tomoya Yamamoto; Sohtaro Komiyama

doi:10.1016/S0385-8146(02)00056-1

Follicular dendritic cell sarcoma of the neck; a case report and literature review

Torahiko Nakashima
, Yuichiro Kuratomi
, Hideki Shiratsuchi
, Hidetaka Yamamoto
, Ryuji Yasumatsu
, Tomoya Yamamoto
, Sohtaro Komiyama

Surgery

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Follicular dendritic cell (FDC) sarcomas, also known as dendritic reticulum cell tumors, are uncommon neoplasms arising from antigen-presenting cells in B-lymphofollicles of nodal and extra-nodal sites. It is considered as an intermediate grade malignancy since it has significant recurrent and metastatic potential. We report a case of FDC sarcoma arising in the neck. A 56-year-old female presented with a left neck tumor. Neck dissection was performed. Microscopically, the tumor showed spindle-shaped stromal cells with large oval and polygonal nuclei. Immunohistologically, the cells were positive for CD21 and CD35, consistent with FDC sarcomas. Adjuvant chemotherapy of cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP) was given. Literature review provides the current information for the diagnosis and treatment of this unusual tumor.

Original language	English
Pages (from-to)	401-403
Number of pages	3
Journal	Auris Nasus Larynx
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/S0385-8146(02)00056-1
Publication status	Published - Oct 1 2002

All Science Journal Classification (ASJC) codes

Surgery
Otorhinolaryngology

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10.1016/S0385-8146(02)00056-1

Cite this

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title = "Follicular dendritic cell sarcoma of the neck; a case report and literature review",

abstract = "Follicular dendritic cell (FDC) sarcomas, also known as dendritic reticulum cell tumors, are uncommon neoplasms arising from antigen-presenting cells in B-lymphofollicles of nodal and extra-nodal sites. It is considered as an intermediate grade malignancy since it has significant recurrent and metastatic potential. We report a case of FDC sarcoma arising in the neck. A 56-year-old female presented with a left neck tumor. Neck dissection was performed. Microscopically, the tumor showed spindle-shaped stromal cells with large oval and polygonal nuclei. Immunohistologically, the cells were positive for CD21 and CD35, consistent with FDC sarcomas. Adjuvant chemotherapy of cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP) was given. Literature review provides the current information for the diagnosis and treatment of this unusual tumor.",

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TY - JOUR

T1 - Follicular dendritic cell sarcoma of the neck; a case report and literature review

AU - Nakashima, Torahiko

AU - Kuratomi, Yuichiro

AU - Shiratsuchi, Hideki

AU - Yamamoto, Hidetaka

AU - Yasumatsu, Ryuji

AU - Yamamoto, Tomoya

AU - Komiyama, Sohtaro

PY - 2002/10/1

Y1 - 2002/10/1

N2 - Follicular dendritic cell (FDC) sarcomas, also known as dendritic reticulum cell tumors, are uncommon neoplasms arising from antigen-presenting cells in B-lymphofollicles of nodal and extra-nodal sites. It is considered as an intermediate grade malignancy since it has significant recurrent and metastatic potential. We report a case of FDC sarcoma arising in the neck. A 56-year-old female presented with a left neck tumor. Neck dissection was performed. Microscopically, the tumor showed spindle-shaped stromal cells with large oval and polygonal nuclei. Immunohistologically, the cells were positive for CD21 and CD35, consistent with FDC sarcomas. Adjuvant chemotherapy of cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP) was given. Literature review provides the current information for the diagnosis and treatment of this unusual tumor.

AB - Follicular dendritic cell (FDC) sarcomas, also known as dendritic reticulum cell tumors, are uncommon neoplasms arising from antigen-presenting cells in B-lymphofollicles of nodal and extra-nodal sites. It is considered as an intermediate grade malignancy since it has significant recurrent and metastatic potential. We report a case of FDC sarcoma arising in the neck. A 56-year-old female presented with a left neck tumor. Neck dissection was performed. Microscopically, the tumor showed spindle-shaped stromal cells with large oval and polygonal nuclei. Immunohistologically, the cells were positive for CD21 and CD35, consistent with FDC sarcomas. Adjuvant chemotherapy of cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP) was given. Literature review provides the current information for the diagnosis and treatment of this unusual tumor.

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U2 - 10.1016/S0385-8146(02)00056-1

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M3 - Article

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AN - SCOPUS:0036775226

SN - 0385-8146

VL - 29

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JO - Auris Nasus Larynx

JF - Auris Nasus Larynx

IS - 4

ER -

Follicular dendritic cell sarcoma of the neck; a case report and literature review

Abstract

All Science Journal Classification (ASJC) codes

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