Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus

B. Sritularak; A. Tantituvanont; P. Chanvorachote; K. Meksawan; T. Miyamoto; Y. Kohno; K. Likhitwitayawuid

Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus

B. Sritularak, A. Tantituvanont, P. Chanvorachote, K. Meksawan, T. Miyamoto, Y. Kohno, K. Likhitwitayawuid

Pharmaceutical Health Care and Sciences

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

A MeOH extract from the stem bark of Artocarpus gomezianus showed DPPH free radical scavenging activity. Bio-assay guided fractionation of this MeOH extract led to the isolation of four flavonoids, namely artonin E (1), cycloartobiloxanthone (2), artobiloxanthone (3) and (+)-catechin (4). These compounds were shown to possess recognizable DPPH free radical scavenging activity and appreciable inhibitory effect on nitric oxide production in murine macrophage-like cells.

Original language	English
Pages (from-to)	387-392
Number of pages	6
Journal	Journal of Medicinal Plants Research
Volume	4
Issue number	5
Publication status	Published - Mar 4 2010

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmaceutical Science
Drug Discovery
Plant Science
Complementary and alternative medicine

Cite this

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abstract = "A MeOH extract from the stem bark of Artocarpus gomezianus showed DPPH free radical scavenging activity. Bio-assay guided fractionation of this MeOH extract led to the isolation of four flavonoids, namely artonin E (1), cycloartobiloxanthone (2), artobiloxanthone (3) and (+)-catechin (4). These compounds were shown to possess recognizable DPPH free radical scavenging activity and appreciable inhibitory effect on nitric oxide production in murine macrophage-like cells.",

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AU - Sritularak, B.

AU - Tantituvanont, A.

AU - Chanvorachote, P.

AU - Meksawan, K.

AU - Miyamoto, T.

AU - Kohno, Y.

AU - Likhitwitayawuid, K.

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N2 - A MeOH extract from the stem bark of Artocarpus gomezianus showed DPPH free radical scavenging activity. Bio-assay guided fractionation of this MeOH extract led to the isolation of four flavonoids, namely artonin E (1), cycloartobiloxanthone (2), artobiloxanthone (3) and (+)-catechin (4). These compounds were shown to possess recognizable DPPH free radical scavenging activity and appreciable inhibitory effect on nitric oxide production in murine macrophage-like cells.

AB - A MeOH extract from the stem bark of Artocarpus gomezianus showed DPPH free radical scavenging activity. Bio-assay guided fractionation of this MeOH extract led to the isolation of four flavonoids, namely artonin E (1), cycloartobiloxanthone (2), artobiloxanthone (3) and (+)-catechin (4). These compounds were shown to possess recognizable DPPH free radical scavenging activity and appreciable inhibitory effect on nitric oxide production in murine macrophage-like cells.

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SN - 1996-0875

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JO - Journal of Medicinal Plants Research

JF - Journal of Medicinal Plants Research

IS - 5

ER -

Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus

Abstract

All Science Journal Classification (ASJC) codes

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