Flavin-trapping of the transient enediolate species formed during glyoxalase I catalysis

Kaori Ueda, Seiji Shinkai, Kenneth T. Douglas

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

A reactive intermediate, probably an enediolate species, has been oxidatively trapped by reaction with added flavin during catalytic turnover by yeast glyoxalase I of the thiohemiacetal from glutathione and phenylglyoxal under anaerobic conditions.

Original languageEnglish
Pages (from-to)371-372
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number6
DOIs
Publication statusPublished - 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Molecular Medicine

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