TY - JOUR
T1 - Femtosecond ionization mass spectrometry for chromatographic detection
AU - Imasaka, Totaro
AU - Imasaka, Tomoko
N1 - Funding Information:
This research was supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science [JSPS KAKENHI Grant Numbers 20H02399] and by the Program of Progress 100 in Kyushu University, The Iwatani Naoji Foundation, and 2020 Collaboration Development Fund for a Joint Program between National Taiwan Normal University and Kyushu University. Quantum chemical calculations were mainly carried out using the computer facilities at the Research Institute for Information Technology, Kyushu University.
Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2021/4/12
Y1 - 2021/4/12
N2 - Mass spectrometry is now in widespread use for the detection of the analytes separated by chromatography. Electron ionization is the most frequently used method in mass spectrometry. However, this ionization technique sometimes suffers from extensive fragmentation of analytes, which makes identification difficult. A photoionization technique has been developed for suppressing this fragmentation and for subsequently observing a molecular ion. A variety of lasers have been employed for the sensitive and selective ionization of organic compounds. A femtosecond laser has a high peak power and is preferential for efficient ionization as well as for suppressing fragmentation, providing valuable information concerning molecular weight and chemical structure as well. In this review, we report on applications of femtosecond ionization mass spectrometry combined with gas chromatography.
AB - Mass spectrometry is now in widespread use for the detection of the analytes separated by chromatography. Electron ionization is the most frequently used method in mass spectrometry. However, this ionization technique sometimes suffers from extensive fragmentation of analytes, which makes identification difficult. A photoionization technique has been developed for suppressing this fragmentation and for subsequently observing a molecular ion. A variety of lasers have been employed for the sensitive and selective ionization of organic compounds. A femtosecond laser has a high peak power and is preferential for efficient ionization as well as for suppressing fragmentation, providing valuable information concerning molecular weight and chemical structure as well. In this review, we report on applications of femtosecond ionization mass spectrometry combined with gas chromatography.
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U2 - 10.1016/j.chroma.2021.462023
DO - 10.1016/j.chroma.2021.462023
M3 - Article
C2 - 33714081
AN - SCOPUS:85102404389
SN - 0021-9673
VL - 1642
JO - Journal of Chromatography A
JF - Journal of Chromatography A
M1 - 462023
ER -