TY - JOUR
T1 - Features of patients with transient monocular blindness
T2 - A multicenter retrospective study in Japan
AU - Tanaka, Koji
AU - Uehara, Toshiyuki
AU - Kimura, Kazumi
AU - Okada, Yasushi
AU - Hasegawa, Yasuhiro
AU - Tanahashi, Norio
AU - Suzuki, Akifumi
AU - Takagi, Shigeharu
AU - Nakagawara, Jyoji
AU - Arii, Kazumasa
AU - Nagahiro, Shinji
AU - Ogasawara, Kuniaki
AU - Nagao, Takehiko
AU - Uchiyama, Shinichiro
AU - Matsumoto, Masayasu
AU - Iihara, Koji
AU - Toyoda, Kazunori
AU - Minematsu, Kazuo
N1 - Funding Information:
Grant support: This study was supported in part by Grants-in-Aid (H20-Junkanki-Ippan-019 and H24-Junkanki-Ippan-011) from the Ministry of Health, Labour and Welfare of Japan (MHLW-Japan) and JSPS KAKENHI (grant number 24591309 ).
PY - 2014/3
Y1 - 2014/3
N2 - Background Transient monocular blindness (TMB) is associated with a transient ischemic attack (TIA). The purpose of this study was to investigate the features of TMB in the Japanese population using data from a multicenter retrospective study of TIA. Methods The subjects were consecutive TIA patients admitted to 13 stroke centers within 7 days after symptom onset. We compared clinical characteristics of patients with TMB and those without TMB who had other symptoms of cerebral TIA. Results A total of 464 patients were registered between January 2008 and December 2009, and 444 patients (283 men, mean age: 68.5 years) were included in the analysis. Thirteen patients (2.9%) presented with TMB. Patients with TMB were less likely to arrive at the specialized stroke center quickly than those without TMB (P =.013). Stenotic lesions in the extracranial internal carotid artery were more common in patients with TMB (33.3% versus 9.1%, P =.022). Conclusions TMB was not common in our TIA inpatients. This study suggests that patients with TMB should immediately undergo a diagnostic workup, including brain and vessel imaging, and cardiac evaluation, as is performed in patients with other cerebral TIA symptoms. A larger, prospective cohort is needed to confirm the risks and outcomes of patients with TMB in the Japanese population.
AB - Background Transient monocular blindness (TMB) is associated with a transient ischemic attack (TIA). The purpose of this study was to investigate the features of TMB in the Japanese population using data from a multicenter retrospective study of TIA. Methods The subjects were consecutive TIA patients admitted to 13 stroke centers within 7 days after symptom onset. We compared clinical characteristics of patients with TMB and those without TMB who had other symptoms of cerebral TIA. Results A total of 464 patients were registered between January 2008 and December 2009, and 444 patients (283 men, mean age: 68.5 years) were included in the analysis. Thirteen patients (2.9%) presented with TMB. Patients with TMB were less likely to arrive at the specialized stroke center quickly than those without TMB (P =.013). Stenotic lesions in the extracranial internal carotid artery were more common in patients with TMB (33.3% versus 9.1%, P =.022). Conclusions TMB was not common in our TIA inpatients. This study suggests that patients with TMB should immediately undergo a diagnostic workup, including brain and vessel imaging, and cardiac evaluation, as is performed in patients with other cerebral TIA symptoms. A larger, prospective cohort is needed to confirm the risks and outcomes of patients with TMB in the Japanese population.
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U2 - 10.1016/j.jstrokecerebrovasdis.2013.09.017
DO - 10.1016/j.jstrokecerebrovasdis.2013.09.017
M3 - Article
C2 - 24144597
AN - SCOPUS:84896372658
SN - 1052-3057
VL - 23
SP - e151-e155
JO - Journal of Stroke and Cerebrovascular Diseases
JF - Journal of Stroke and Cerebrovascular Diseases
IS - 3
ER -