Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus

Naoki Sakane, Kazuhiko Kotani, Kokoro Tsuzaki, Masami Nishi, Kaoru Takahashi, Takashi Murata, Kazunori Yamada, Kentaro Okazaki, Katsuyuki Yanagisawa, Kenichi Yamada, Nobuichi Kuribayashi, Yasuo Totsuka, Toru Hiyoshi, Motoji Naka, Masatake Sugimoto, Yuji Aoki, Masako Waki, Miyuki Furuya, Haruko Kitaoka, Mariko OishiIkki Shimizu, Hiroaki Miyaoka, Akira Okada, Toshikazu Yamamoto

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin-treated patients with type 2 diabetes mellitus. A questionnaire survey on hypoglycemia and patient-physician communication was carried out in 355 patients with insulin-treated type 2 diabetes mellitus patients at 16 hospitals and clinics. A fear of hypoglycemia was reported by 27.7% of patients. A stepwise logistic regression analysis found that severe hypoglycemia during the past 1 year was a significant determinant of fear of hypoglycemia (odds ratio 2.16, 95% confidence interval 1.06-4.41; P = 0.034), and age (odds ratio 1.02, 95% confidence interval 1.00-1.05, P = 0.038) and living alone (odds ratio 1.93, 95% confidence interval 1.00-3.73, P < 0.05) were significantly higher in patients with fear of hypoglycemia than in those without it.

Original languageEnglish
Pages (from-to)567-570
Number of pages4
JournalJournal of Diabetes Investigation
Volume6
Issue number5
DOIs
Publication statusPublished - Sept 1 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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