TY - JOUR
T1 - Factors associated with onset-to-door time in patients with transient ischemic attack admitted to stroke centers
AU - Uehara, Toshiyuki
AU - Kimura, Kazumi
AU - Okada, Yasushi
AU - Hasegawa, Yasuhiro
AU - Tanahashi, Norio
AU - Suzuki, Akifumi
AU - Takagi, Shigeharu
AU - Nakagawara, Jyoji
AU - Arii, Kazumasa
AU - Nagahiro, Shinji
AU - Ogasawara, Kuniaki
AU - Nagao, Takehiko
AU - Uchiyama, Shinichiro
AU - Matsumoto, Masayasu
AU - Iihara, Koji
AU - Minematsu, Kazuo
PY - 2014/2
Y1 - 2014/2
N2 - Background and Purpose - The aim of this study was to elucidate the factors associated with the time from symptom onset to arrival at a stroke center (onset-to-door time [ODT]) in patients with classically defined transient ischemic attack using data from a multicenter, retrospective study. Methods - The subjects were patients with transient ischemic attack admitted to 13 stroke centers in Japan within 7 days of onset between 2008 and 2009. A total of 464 patients registered (292 men, 68.5±13.2 years old), and 421 of them (268 men, 68.8±13.1 years old) were included in the analyses. ODT was classified into the following 5 categories: <3 hours, 3 to 6 hours, 7 to 12 hours, 13 to 24 hours, and >24 hours. Results - There were 233 patients (55.3%) who visited a stroke center within 3 hours of symptom onset. Multiple ordinal logistic regression analysis revealed that motor weakness, speech disturbance, and duration of symptoms >10 minutes were independently associated with a short ODT. Furthermore, a history of transient ischemic attack and hypertension and a referral from another medical facility were independently associated with a long ODT. Patients with a higher ABCD 2 score were likely to arrive at a stroke center more quickly. Conclusions - We identified several factors that were positively and negatively associated with the ODT in patients with transient ischemic attack.
AB - Background and Purpose - The aim of this study was to elucidate the factors associated with the time from symptom onset to arrival at a stroke center (onset-to-door time [ODT]) in patients with classically defined transient ischemic attack using data from a multicenter, retrospective study. Methods - The subjects were patients with transient ischemic attack admitted to 13 stroke centers in Japan within 7 days of onset between 2008 and 2009. A total of 464 patients registered (292 men, 68.5±13.2 years old), and 421 of them (268 men, 68.8±13.1 years old) were included in the analyses. ODT was classified into the following 5 categories: <3 hours, 3 to 6 hours, 7 to 12 hours, 13 to 24 hours, and >24 hours. Results - There were 233 patients (55.3%) who visited a stroke center within 3 hours of symptom onset. Multiple ordinal logistic regression analysis revealed that motor weakness, speech disturbance, and duration of symptoms >10 minutes were independently associated with a short ODT. Furthermore, a history of transient ischemic attack and hypertension and a referral from another medical facility were independently associated with a long ODT. Patients with a higher ABCD 2 score were likely to arrive at a stroke center more quickly. Conclusions - We identified several factors that were positively and negatively associated with the ODT in patients with transient ischemic attack.
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U2 - 10.1161/STROKEAHA.113.003367
DO - 10.1161/STROKEAHA.113.003367
M3 - Article
C2 - 24262324
AN - SCOPUS:84893652562
SN - 0039-2499
VL - 45
SP - 611
EP - 613
JO - Stroke
JF - Stroke
IS - 2
ER -