Fabrication of bone cement that fully transforms to carbonate apatite

Arief Cahyanto, Michito Maruta, Kanji Tsuru, Shigeki Matsuya, Kunio Ishikawa

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)


The objective of this study was to fabricate a type of bone cement that could fully transform to carbonate apatite (CO3Ap) in physiological conditions. A combination of calcium carbonate (CaCO3) and dicalcium phosphate anhydrous was chosen as the powder phase and mixed with one of three kinds of sodium phosphate solutions: NaH2PO4, Na2HPO4, or Na3PO4. The cement that fully transformed to CO3Ap was fabricated using vaterite, instead of calcite, as a CaCO3 source. Their stability in aqueous solutions was different, regardless of the type of sodium phosphate solution. Rate of transformation to CO3Ap in descending order was Na3PO4>Na2HPO4>NaH2PO4. Transformation rate could be affected by the pH of solution. Results of this study showed that it was advantageous to use vaterite to fabricate CO3Ap-forming cement.

Original languageEnglish
Pages (from-to)394-401
Number of pages8
Journaldental materials journal
Issue number3
Publication statusPublished - Apr 23 2015

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • General Dentistry


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