TY - JOUR
T1 - Fabrication of β-TCP foam
T2 - Effects of magnesium oxide as phase stabilizer on its properties
AU - Nikaido, Taro
AU - Tsuru, Kanji
AU - Munar, Melvin
AU - Maruta, Michito
AU - Matsuya, Shigeki
AU - Nakamura, Seiji
AU - Ishikawa, Kunio
N1 - Funding Information:
This study was supported in part by the Strategic Promotion of Innovative Research (Grant No. AJ120495) and Development Program of the Japan Agency for Medical Research (Grant No. 25893175) .
Publisher Copyright:
© 2015 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
PY - 2015/5/7
Y1 - 2015/5/7
N2 - Porous β-tricalcium phosphate (β-TCP) has attracted attention as an artificial bone substitute. α-TCP foam that mimics the fully interconnected porous structure of the cancellous bone can be fabricated by a ceramics foam method, which requires sintering at high temperature. However, β-TCP foam could not be fabricated by the ceramics foam method since the sintering temperature required is above the αβ transition temperature. To fabricate the β-TCP foam that mimics the fully interconnected porous structure of cancellous bone, magnesium oxide (MgO) is added as a phase stabilizer. β-TCP foam was obtained when at least 3 mol% MgO was added. Lattice parameter analysis revealed that the MgO as a β-phase stabilizer was incorporated into the lattice of the TCP structure. The porosity of the β-TCP foam containing 3 mol% MgO was 92%, and the compressive strength was approximately 32 kPa. Despite the observed smooth surface and lower porosity of β-TCP foam compared to α-TCP foam, no improvement on the compressive strength of β-TCP foam occurred even by the addition of 3 mol% or more of MgO. Formation of micro-cracks could be one the reasons. These micro-cracks were formed by contraction as a result from growth of adjacent grains.
AB - Porous β-tricalcium phosphate (β-TCP) has attracted attention as an artificial bone substitute. α-TCP foam that mimics the fully interconnected porous structure of the cancellous bone can be fabricated by a ceramics foam method, which requires sintering at high temperature. However, β-TCP foam could not be fabricated by the ceramics foam method since the sintering temperature required is above the αβ transition temperature. To fabricate the β-TCP foam that mimics the fully interconnected porous structure of cancellous bone, magnesium oxide (MgO) is added as a phase stabilizer. β-TCP foam was obtained when at least 3 mol% MgO was added. Lattice parameter analysis revealed that the MgO as a β-phase stabilizer was incorporated into the lattice of the TCP structure. The porosity of the β-TCP foam containing 3 mol% MgO was 92%, and the compressive strength was approximately 32 kPa. Despite the observed smooth surface and lower porosity of β-TCP foam compared to α-TCP foam, no improvement on the compressive strength of β-TCP foam occurred even by the addition of 3 mol% or more of MgO. Formation of micro-cracks could be one the reasons. These micro-cracks were formed by contraction as a result from growth of adjacent grains.
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U2 - 10.1016/j.ceramint.2015.07.053
DO - 10.1016/j.ceramint.2015.07.053
M3 - Article
AN - SCOPUS:84955395127
SN - 0272-8842
VL - 41
SP - 14245
EP - 14250
JO - Ceramics International
JF - Ceramics International
IS - 10
ER -