TY - GEN
T1 - Extension and measurements on multicomponent phospholipid vesicles by use of dual-beam optical tweezers
AU - Ichikawa, Masatoshi
AU - Shitamichi, Yoko
AU - Kimura, Yasuyuki
PY - 2009
Y1 - 2009
N2 - A micrometer-sized giant vesicle is studied by extending from the inside by using dual-beam optical tweezers in order to measure mechanical properties such as bending rigidity and surface tension of the membrane. As a micrometer-sized vesicle is extended, its shape gradually changes from a sphere to a lemon-shape, and discretely the lemon-shape deforms into a shape of a tube beside a sphere or a lemon part. The surface tension and the bending rigidity of the lipid membrane are obtained from the measured force-extension curve. In the one-phase vesicle, it is found that the surface tension is increasing as the charged component increasing, but the bending rigidity remains almost constant. In the phase-separated vesicle, the characteristic deformation different from one in the one-phase vesicle has been observed.
AB - A micrometer-sized giant vesicle is studied by extending from the inside by using dual-beam optical tweezers in order to measure mechanical properties such as bending rigidity and surface tension of the membrane. As a micrometer-sized vesicle is extended, its shape gradually changes from a sphere to a lemon-shape, and discretely the lemon-shape deforms into a shape of a tube beside a sphere or a lemon part. The surface tension and the bending rigidity of the lipid membrane are obtained from the measured force-extension curve. In the one-phase vesicle, it is found that the surface tension is increasing as the charged component increasing, but the bending rigidity remains almost constant. In the phase-separated vesicle, the characteristic deformation different from one in the one-phase vesicle has been observed.
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U2 - 10.1109/MHS.2009.5351928
DO - 10.1109/MHS.2009.5351928
M3 - Conference contribution
AN - SCOPUS:77950958025
SN - 9781424450954
T3 - 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
SP - 170
EP - 175
BT - 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
T2 - 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
Y2 - 8 November 2009 through 11 November 2009
ER -