Experimental Evidence of Slow Mode Water in the Vicinity of Poly(ethylene oxide) at Physiological Temperature

Taiki Tominaga, Mafumi Hishida, Daiki Murakami, Yoshihisa Fujii, Masaru Tanaka, Hideki Seto

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

In some synthetic polymers used for medical applications, hydration water in the vicinity of the polymer chains is known to play an important role in biocompatibility and is referred to as intermediate water. The crystallization of water below 0 °C observed during thermal analysis has been considered as evidence of the presence of intermediate water. However, the origin and physicochemical properties of intermediate water have not yet been elucidated. In this study, as a typical biocompatible polymer, poly(ethylene oxide) and its hydration water were investigated with the use of terahertz time-domain spectroscopy and quasi-elastic neutron scattering. The obtained results prove the existence of a significant amount of mobile water that interacts with the polymer chains even when the water content is low at physiological temperatures.

Original languageEnglish
Pages (from-to)1758-1767
Number of pages10
JournalJournal of Physical Chemistry B
Volume126
Issue number8
DOIs
Publication statusPublished - Mar 3 2022

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films
  • Materials Chemistry

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