Evaluation of protein function on structurally controlled stereocomplex thin films

Yuya Nagasaka; Hisao Matsuno; Kimio Kurita; Takeshi Serizawa

Evaluation of protein function on structurally controlled stereocomplex thin films

Yuya Nagasaka, Hisao Matsuno, Kimio Kurita, Takeshi Serizawa

Research output: Contribution to conference › Paper › peer-review

Abstract

Isotactic and syndiotactic poly(methyl methacrylate)s (PMMAs) form double-stranded helical stereocomplexes with a respective length ratio of 1:2 based on van der Waals interactions in organic solvents. Bioactivities of stereocomplex surfaces are significant for determining the potential for biomedical applications. We prepared PMMA stereocomplex films by a layer-by-layer assembly method, and observed antigen-antibody interactions and enzyme reactions on film surfaces. Effects of film surface structures on antigen-antibody interactions and enzyme reactions were investigated. As a result, it was found that protein activities on stereocomplex films were higher than those on PMMA homogeneous films.

Original language	English
Pages	4274-4275
Number of pages	2
Publication status	Published - Dec 1 2006
Externally published	Yes
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: Sept 20 2006 → Sept 22 2006

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
Country/Territory	Japan
City	Toyama
Period	9/20/06 → 9/22/06

All Science Journal Classification (ASJC) codes

Engineering(all)

Cite this

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title = "Evaluation of protein function on structurally controlled stereocomplex thin films",

abstract = "Isotactic and syndiotactic poly(methyl methacrylate)s (PMMAs) form double-stranded helical stereocomplexes with a respective length ratio of 1:2 based on van der Waals interactions in organic solvents. Bioactivities of stereocomplex surfaces are significant for determining the potential for biomedical applications. We prepared PMMA stereocomplex films by a layer-by-layer assembly method, and observed antigen-antibody interactions and enzyme reactions on film surfaces. Effects of film surface structures on antigen-antibody interactions and enzyme reactions were investigated. As a result, it was found that protein activities on stereocomplex films were higher than those on PMMA homogeneous films.",

author = "Yuya Nagasaka and Hisao Matsuno and Kimio Kurita and Takeshi Serizawa",

year = "2006",

month = dec,

day = "1",

language = "English",

pages = "4274--4275",

note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

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TY - CONF

T1 - Evaluation of protein function on structurally controlled stereocomplex thin films

AU - Nagasaka, Yuya

AU - Matsuno, Hisao

AU - Kurita, Kimio

AU - Serizawa, Takeshi

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Isotactic and syndiotactic poly(methyl methacrylate)s (PMMAs) form double-stranded helical stereocomplexes with a respective length ratio of 1:2 based on van der Waals interactions in organic solvents. Bioactivities of stereocomplex surfaces are significant for determining the potential for biomedical applications. We prepared PMMA stereocomplex films by a layer-by-layer assembly method, and observed antigen-antibody interactions and enzyme reactions on film surfaces. Effects of film surface structures on antigen-antibody interactions and enzyme reactions were investigated. As a result, it was found that protein activities on stereocomplex films were higher than those on PMMA homogeneous films.

AB - Isotactic and syndiotactic poly(methyl methacrylate)s (PMMAs) form double-stranded helical stereocomplexes with a respective length ratio of 1:2 based on van der Waals interactions in organic solvents. Bioactivities of stereocomplex surfaces are significant for determining the potential for biomedical applications. We prepared PMMA stereocomplex films by a layer-by-layer assembly method, and observed antigen-antibody interactions and enzyme reactions on film surfaces. Effects of film surface structures on antigen-antibody interactions and enzyme reactions were investigated. As a result, it was found that protein activities on stereocomplex films were higher than those on PMMA homogeneous films.

UR - http://www.scopus.com/inward/record.url?scp=33846147654&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846147654&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33846147654

SP - 4274

EP - 4275

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Evaluation of protein function on structurally controlled stereocomplex thin films

Abstract

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All Science Journal Classification (ASJC) codes

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