TY - GEN
T1 - Evaluation of pluripotency in human intenstinal cells by microfluidic-based single cell deformability analysis
AU - Terada, Miyu
AU - Ide, Sachiko
AU - Naito, Toyohiro
AU - Matsusaki, Michiya
AU - Kaji, Noritada
N1 - Publisher Copyright:
© 2020 CBMS-0001
PY - 2020
Y1 - 2020
N2 - In this study, we have developed a microfluidic device that can analyze the pluripotency of cells by measuring the cell deformability based on ionic current sensing at a single cell level. We successfully identified human colon cancer cells (HT29) with high and low pluripotency based on the deformability information and the result was confirmed by a biochemical assay, Aldehyde Dehydrogenase (ALDH) assay, which is an important biomarker of the pluripotency.
AB - In this study, we have developed a microfluidic device that can analyze the pluripotency of cells by measuring the cell deformability based on ionic current sensing at a single cell level. We successfully identified human colon cancer cells (HT29) with high and low pluripotency based on the deformability information and the result was confirmed by a biochemical assay, Aldehyde Dehydrogenase (ALDH) assay, which is an important biomarker of the pluripotency.
UR - http://www.scopus.com/inward/record.url?scp=85098242781&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85098242781&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85098242781
T3 - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 1049
EP - 1050
BT - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
Y2 - 4 October 2020 through 9 October 2020
ER -
