TY - JOUR
T1 - Establishment of a Feline T-Lymphoblastoid Cell Line Susceptible to Feline Immunodeficiency Viruses
AU - Fujimoto, Satoshi
AU - Masuda, Mahito
AU - Ono, Etsuro
AU - Kida, Hiroshi
AU - Shimizu, Yukio
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 1993
Y1 - 1993
N2 - A feline T-lymphoblastoid cell line susceptible to feline immunodeficiency viruses (FIV) was established and designated as Yu-1 cells. Yu-1 cells continued to grow over one year with more than 100 successive passages in the presence of human recombinant interleukin-2. Surface antigens of Yu-1 cells were feline Pan-T+, CD4+, and CD8-. Susceptibility of Yu-1 cells to FIV strains were higher than that of the primary culture of the feline peripheral blood mononuclear cells, indicating that this cell line should be useful for isolation, propagation, and neutralization test of FIV.
AB - A feline T-lymphoblastoid cell line susceptible to feline immunodeficiency viruses (FIV) was established and designated as Yu-1 cells. Yu-1 cells continued to grow over one year with more than 100 successive passages in the presence of human recombinant interleukin-2. Surface antigens of Yu-1 cells were feline Pan-T+, CD4+, and CD8-. Susceptibility of Yu-1 cells to FIV strains were higher than that of the primary culture of the feline peripheral blood mononuclear cells, indicating that this cell line should be useful for isolation, propagation, and neutralization test of FIV.
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U2 - 10.1111/j.1348-0421.1993.tb03231.x
DO - 10.1111/j.1348-0421.1993.tb03231.x
M3 - Article
C2 - 7689139
AN - SCOPUS:0027239605
SN - 0385-5600
VL - 37
SP - 415
EP - 418
JO - MICROBIOLOGY and IMMUNOLOGY
JF - MICROBIOLOGY and IMMUNOLOGY
IS - 5
ER -