CD1 antigens are classified into at least three groups, CD1a, CD1b, and CD1c. In order to delineate the localization of epitopes of CD 1 antigens in human skin, we examined the immunoreactivity of fourteen different CD1 antibodies (seven CDla, five CD1b, and two CD1c antibodies). The epitopes for CD1a, CD1b, and CD1c are differentially localized on epidermal Langerhans cells, dermal dendritic cells, keratinocytes, the luminal portion of eccrine gland ducts, and the basement membrane zone in normal human skin.
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology