Enzymological evidence for cannabichromenic acid biosynthesis

S. Morimoto; K. Komatsu; F. Taura; Y. Shoyama

doi:10.1021/np970210y

Enzymological evidence for cannabichromenic acid biosynthesis

S. Morimoto, K. Komatsu, F. Taura, Y. Shoyama

Pharmaceutical Health Care and Sciences

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55 Citations (Scopus)

Abstract

An enzyme involved in the biosynthesis of cannabichromenic acid was identified in young leaves of Cannabis sativa. The enzyme, named cannabichromenic acid synthase, catalyzed the oxidocyclization of cannabigerolic acid to cannabichromenic acid. The biosynthetic mechanism for the formation of cannabichromenic acid was similar to those of Δ¹- tetrahydrocar nabinolic acid and cannabidiolic acid.

Original language	English
Pages (from-to)	854-867
Number of pages	14
Journal	Journal of Natural Products
Volume	60
Issue number	8
DOIs	https://doi.org/10.1021/np970210y
Publication status	Published - 1997

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np970210y

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abstract = "An enzyme involved in the biosynthesis of cannabichromenic acid was identified in young leaves of Cannabis sativa. The enzyme, named cannabichromenic acid synthase, catalyzed the oxidocyclization of cannabigerolic acid to cannabichromenic acid. The biosynthetic mechanism for the formation of cannabichromenic acid was similar to those of Δ1- tetrahydrocar nabinolic acid and cannabidiolic acid.",

author = "S. Morimoto and K. Komatsu and F. Taura and Y. Shoyama",

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AU - Morimoto, S.

AU - Komatsu, K.

AU - Taura, F.

AU - Shoyama, Y.

PY - 1997

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N2 - An enzyme involved in the biosynthesis of cannabichromenic acid was identified in young leaves of Cannabis sativa. The enzyme, named cannabichromenic acid synthase, catalyzed the oxidocyclization of cannabigerolic acid to cannabichromenic acid. The biosynthetic mechanism for the formation of cannabichromenic acid was similar to those of Δ1- tetrahydrocar nabinolic acid and cannabidiolic acid.

AB - An enzyme involved in the biosynthesis of cannabichromenic acid was identified in young leaves of Cannabis sativa. The enzyme, named cannabichromenic acid synthase, catalyzed the oxidocyclization of cannabigerolic acid to cannabichromenic acid. The biosynthetic mechanism for the formation of cannabichromenic acid was similar to those of Δ1- tetrahydrocar nabinolic acid and cannabidiolic acid.

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Enzymological evidence for cannabichromenic acid biosynthesis

Abstract

All Science Journal Classification (ASJC) codes

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