TY - JOUR
T1 - Enhanced release of cholecystokinin by soya-bean trypsin inhibitor in chickens
AU - Furuse, M.
AU - Yang, S. I.
AU - Muramatsu, T.
AU - Okumura, J.
N1 - Funding Information:
This study was supported by grant-in-aid 01480099 for scientific research from the Ministry of Education, Science, and Culture in Japan.
PY - 1990
Y1 - 1990
N2 - Whether ingestion of soya-bean trypsin inhibitor (SBTI) alters the release of cholecystokinin (CCK) was investigated in chickens. A meal of an adequate diet supplemented with SBTI (0, 100, or 1000 mg/kg) was given through a stomach tube, followed by CCK determination with specific CCK-8 antibody. The plasma CCK level increased from a basal level (control diet) of 9.6 ± 0.6 to 13.4 ± 0.6 and 18.1 ± 0.8 fmol/ml plasma at 90 min after feeding the diet supplemented with 100 and 1000 mg SBTI, respectively. Since the SBTI supplementation did not affect crop emptying rates significantly, it was concluded that SBTI by itself enhanced CCK release into circulation in a dose-dependent fashion.
AB - Whether ingestion of soya-bean trypsin inhibitor (SBTI) alters the release of cholecystokinin (CCK) was investigated in chickens. A meal of an adequate diet supplemented with SBTI (0, 100, or 1000 mg/kg) was given through a stomach tube, followed by CCK determination with specific CCK-8 antibody. The plasma CCK level increased from a basal level (control diet) of 9.6 ± 0.6 to 13.4 ± 0.6 and 18.1 ± 0.8 fmol/ml plasma at 90 min after feeding the diet supplemented with 100 and 1000 mg SBTI, respectively. Since the SBTI supplementation did not affect crop emptying rates significantly, it was concluded that SBTI by itself enhanced CCK release into circulation in a dose-dependent fashion.
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U2 - 10.3109/00365529008998560
DO - 10.3109/00365529008998560
M3 - Article
C2 - 2274745
AN - SCOPUS:0025644459
SN - 0036-5521
VL - 25
SP - 1242
EP - 1246
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
IS - 12
ER -