Endoscopic band ligation therapy for upper gastrointestinal bleeding related to Mallory-Weiss syndrome

N. Higuchi, K. Akahoshi, Y. Sumida, M. Kubokawa, Y. Motomura, M. Kimura, M. Matsumoto, K. Nakamura, H. Nawata

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23 Citations (Scopus)


Background: No consensus exists as to the best endoscopic treatment for Mallory-Weiss syndrome. Endoscopic band ligation is a readily available and easily learned technique. This prospective study evaluated the efficacy and safety of endoscopic band ligation therapy for Mallory-Weiss syndrome. Methods: From August 1998 to June 2005, a clinical trial assessed 37 patients with a diagnosis of Mallory-Weiss syndrome who had active bleeding, exposed vessels, or both. Their lesions were treated using endoscopic band ligation. Results: Endoscopic band ligation was successful in 36 of 37 cases, with a follow-up period ranging from 1 to 24 months. The remaining patient had severe liver failure and disseminated intravascular coagulation. The patient bled again at 12 h and subsequently died. Except for this case, no recurrent bleeding, perforation, or other complications occurred. Conclusions: The study results suggest that endoscopic band ligation is an effective, safe, and easily learned procedure for treating upper gastrointestinal bleeding related to Mallory-Weiss syndrome.

Original languageEnglish
Pages (from-to)1431-1434
Number of pages4
JournalSurgical Endoscopy and Other Interventional Techniques
Issue number9
Publication statusPublished - Sept 2006

All Science Journal Classification (ASJC) codes

  • Surgery


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