Enantioselective Michael reaction of ketone lithium enolates using a chiral ligand

Kosuke Yasuda; Mitsuru Shindo; Kenji Koga

doi:10.1016/0040-4039(96)01367-6

Enantioselective Michael reaction of ketone lithium enolates using a chiral ligand

Kosuke Yasuda, Mitsuru Shindo, Kenji Koga

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

The enantioselective Michael reaction of ketone lithium enolates using a chiral amine ligand (1) was studied. Michael adducts (4) of up to 94% ee were obtained by the reaction between methyl ketones (2) and Michael acceptors (3) having a benzylidene group.

Original language	English
Pages (from-to)	6343-6346
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	35
DOIs	https://doi.org/10.1016/0040-4039(96)01367-6
Publication status	Published - Aug 26 1996
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(96)01367-6

Cite this

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title = "Enantioselective Michael reaction of ketone lithium enolates using a chiral ligand",

abstract = "The enantioselective Michael reaction of ketone lithium enolates using a chiral amine ligand (1) was studied. Michael adducts (4) of up to 94% ee were obtained by the reaction between methyl ketones (2) and Michael acceptors (3) having a benzylidene group.",

author = "Kosuke Yasuda and Mitsuru Shindo and Kenji Koga",

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AU - Yasuda, Kosuke

AU - Shindo, Mitsuru

AU - Koga, Kenji

PY - 1996/8/26

Y1 - 1996/8/26

N2 - The enantioselective Michael reaction of ketone lithium enolates using a chiral amine ligand (1) was studied. Michael adducts (4) of up to 94% ee were obtained by the reaction between methyl ketones (2) and Michael acceptors (3) having a benzylidene group.

AB - The enantioselective Michael reaction of ketone lithium enolates using a chiral amine ligand (1) was studied. Michael adducts (4) of up to 94% ee were obtained by the reaction between methyl ketones (2) and Michael acceptors (3) having a benzylidene group.

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M3 - Article

AN - SCOPUS:0030603064

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

Enantioselective Michael reaction of ketone lithium enolates using a chiral ligand

Abstract

All Science Journal Classification (ASJC) codes

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