TY - JOUR
T1 - Enantioselective esterification of glycidol by surfactant-lipase complexes in organic media
AU - Okazaki, Shin Ya
AU - Kamiya, Noriho
AU - Goto, Masahiro
AU - Nakashio, Fumiyuki
N1 - Funding Information:
We are grateful to Amano Pharmaceutical Co., Ltd., for generously providing lipases. This work was supported by a Grant-in-Aid for Scientific Research (No. 07555245) from the Ministry of Education, Science, Sports and Culture of Japan.
PY - 1997
Y1 - 1997
N2 - Enantioselective esterification of glycidol has been performed with lauric acid in organic media dosed with surfactant-lipase complexes as catalysts. Lipase derived from various biomaterial sources was complexed with nonionic surfactant, dioleyl-N-D-glucono-L-glutamate, prior to use. Surfactant-lipase D (from Rhizopus delemar) complex had a higher enantioselectivity (v(R)/v(S) = 7.6) than the other lipases and the corresponding initial reaction rate was averaging 100-fold better than that of native powder lipase D in cyclohexane at 35°C.
AB - Enantioselective esterification of glycidol has been performed with lauric acid in organic media dosed with surfactant-lipase complexes as catalysts. Lipase derived from various biomaterial sources was complexed with nonionic surfactant, dioleyl-N-D-glucono-L-glutamate, prior to use. Surfactant-lipase D (from Rhizopus delemar) complex had a higher enantioselectivity (v(R)/v(S) = 7.6) than the other lipases and the corresponding initial reaction rate was averaging 100-fold better than that of native powder lipase D in cyclohexane at 35°C.
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U2 - 10.1023/A:1018337320213
DO - 10.1023/A:1018337320213
M3 - Article
AN - SCOPUS:0030957365
SN - 0141-5492
VL - 19
SP - 541
EP - 543
JO - Biotechnology letters
JF - Biotechnology letters
IS - 6
ER -