Enantioselective catalytic ring opening of epoxides with carboxylic acids

Eric N. Jacobsen; Fumitoshi Kakiuchi; Reed G. Konsler; Jay F. Larrow; Makoto Tokunaga

doi:10.1016/S0040-4039(96)02414-8

Enantioselective catalytic ring opening of epoxides with carboxylic acids

Eric N. Jacobsen, Fumitoshi Kakiuchi, Reed G. Konsler, Jay F. Larrow, Makoto Tokunaga

Research output: Contribution to journal › Article › peer-review

282 Citations (Scopus)

Abstract

The chiral Co(salen) complex 3 is an effective catalyst for the asymmetric ring-opening of meso epoxides with benzoic acid. Enantioselectivities of 55-93% were obtained with a range of substrates.

Original language	English
Pages (from-to)	773-776
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	5
DOIs	https://doi.org/10.1016/S0040-4039(96)02414-8
Publication status	Published - Feb 3 1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(96)02414-8

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title = "Enantioselective catalytic ring opening of epoxides with carboxylic acids",

abstract = "The chiral Co(salen) complex 3 is an effective catalyst for the asymmetric ring-opening of meso epoxides with benzoic acid. Enantioselectivities of 55-93% were obtained with a range of substrates.",

author = "Jacobsen, {Eric N.} and Fumitoshi Kakiuchi and Konsler, {Reed G.} and Larrow, {Jay F.} and Makoto Tokunaga",

note = "Funding Information: Acknowledgments: This work was supported by the National Institutes of Health (GM-43214), and by postdoctoral fellowship support from the Japan Society for the Promotion of Science to M.T. and F.K.",

year = "1997",

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doi = "10.1016/S0040-4039(96)02414-8",

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journal = "Tetrahedron Letters",

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T1 - Enantioselective catalytic ring opening of epoxides with carboxylic acids

AU - Jacobsen, Eric N.

AU - Kakiuchi, Fumitoshi

AU - Konsler, Reed G.

AU - Larrow, Jay F.

AU - Tokunaga, Makoto

N1 - Funding Information: Acknowledgments: This work was supported by the National Institutes of Health (GM-43214), and by postdoctoral fellowship support from the Japan Society for the Promotion of Science to M.T. and F.K.

PY - 1997/2/3

Y1 - 1997/2/3

N2 - The chiral Co(salen) complex 3 is an effective catalyst for the asymmetric ring-opening of meso epoxides with benzoic acid. Enantioselectivities of 55-93% were obtained with a range of substrates.

AB - The chiral Co(salen) complex 3 is an effective catalyst for the asymmetric ring-opening of meso epoxides with benzoic acid. Enantioselectivities of 55-93% were obtained with a range of substrates.

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U2 - 10.1016/S0040-4039(96)02414-8

DO - 10.1016/S0040-4039(96)02414-8

M3 - Article

AN - SCOPUS:0031024261

SN - 0040-4039

VL - 38

SP - 773

EP - 776

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 5

ER -

Enantioselective catalytic ring opening of epoxides with carboxylic acids

Abstract

All Science Journal Classification (ASJC) codes

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