Efficient synthesis of 6-substituted purine derivatives using Pd-catalyzed cross-coupling reactions with 2'-deoxyguanosine O⁶-tosylate

Chemistry

• Cross-Coupling Reaction 100%
• Synthesis (Chemical) 66%
• Purine 66%
• Number 33%
• Reaction Selectivity 33%
• Transition-Metal Catalyst 33%
• Oligonucleotide 33%
• Nucleoside Analogue 33%
• Bioactivity 33%
• Grignard Reagent 33%
• Boronic Acid 33%
• Guanosine 33%
• Cytosine 33%
• Ligand 33%