TY - JOUR
T1 - Effects of transcranial magnetic stimulation on EEG activity
AU - Iramina, Keiji
AU - Maeno, Takashi
AU - Kowatari, Yasuyuki
AU - Ueno, Shoogo
N1 - Funding Information:
Manuscript received February 19, 2002; revised May 20, 2002. This work was supported in part by Grant-in Aid 12002002 for Scientific Research, Ministry of Education, Science, Sports, Culture and Technology, Japan. The authors are with the Department of Biomedical Engineering, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan (e-mail: iramina@medes.m.u-tokyo.ac.jp). Digital Object Identifier 10.1109/TMAG.2002.802309.
PY - 2002/9
Y1 - 2002/9
N2 - The combination of transcranial magnetic stimula tion (TMS) and electroencephalogram (EEG) is an effective tool for investigating the functional connectivity in the brain. This paper investigated cortical reactivity and connectivity by the combination of TMS and EEG. Spontaneous activity of the brain was measured before and after magnetic stimulation. The effect of TMS on alpha activity was investigated. The alpha wave was suppressed for a few seconds after stimulation of the occipital area. No differences in the suppression of the alpha waves were found with and without auditory masking. Furthermore, the coil click of TMS had no effect on the alpha wave. The alpha wave was significantly suppressed by the occipital stimulation, whereas slight suppression was observed in other areas of stimulation. The alpha wave was increasingly suppressed as the stimulation magnitude became more intense. In order to investigate the evoked response by TMS, evoked potentials generated by TMS were measured. It was observed that more evoked responses spread to the center of the brain when the cerebellum was stimulated than at other areas of stimulation. These results indicated that TMS blocked the neural connections within alpha wave generation, and the electrical currents produced by TMS affected the neural activities.
AB - The combination of transcranial magnetic stimula tion (TMS) and electroencephalogram (EEG) is an effective tool for investigating the functional connectivity in the brain. This paper investigated cortical reactivity and connectivity by the combination of TMS and EEG. Spontaneous activity of the brain was measured before and after magnetic stimulation. The effect of TMS on alpha activity was investigated. The alpha wave was suppressed for a few seconds after stimulation of the occipital area. No differences in the suppression of the alpha waves were found with and without auditory masking. Furthermore, the coil click of TMS had no effect on the alpha wave. The alpha wave was significantly suppressed by the occipital stimulation, whereas slight suppression was observed in other areas of stimulation. The alpha wave was increasingly suppressed as the stimulation magnitude became more intense. In order to investigate the evoked response by TMS, evoked potentials generated by TMS were measured. It was observed that more evoked responses spread to the center of the brain when the cerebellum was stimulated than at other areas of stimulation. These results indicated that TMS blocked the neural connections within alpha wave generation, and the electrical currents produced by TMS affected the neural activities.
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U2 - 10.1109/TMAG.2002.802309
DO - 10.1109/TMAG.2002.802309
M3 - Conference article
AN - SCOPUS:0036762466
SN - 0018-9464
VL - 38
SP - 3347
EP - 3349
JO - IEEE Transactions on Magnetics
JF - IEEE Transactions on Magnetics
IS - 5 I
T2 - 2002 International Magnetics Conference (Intermag 2002)
Y2 - 28 April 2002 through 2 May 2002
ER -