Effects of stereochemistry of sugars on protein stabilities

Kiyonari Masumoto, Tadashi Ueda, Makiko Nagata, Yuko Yamada, Yuichiro Yoshida, Yoshio Hashimoto, Taiji Imoto

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


We investigated thermal stabilities of four proteins in the presence of four kinds of sugars to analyze the mechanism of stabilization of proteins by additives. These proteins were stabilized by the addition of sugars, and the degree of stabilization correlated to the partial molar isentropic compressibility of the sugar.

Original languageEnglish
Pages (from-to)435-439
Number of pages5
JournalProtein and Peptide Letters
Issue number5
Publication statusPublished - 2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Biochemistry


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