Effect of pre-firing compression on the prevention of pancreatic fistula in distal pancreatectomy

Teijiro Hirashita, Masayuki Ohta, Kazuhiro Yada, Kazuhiro Tada, Kunihiro Saga, Hiroomi Takayama, Yuichi Endo, Hiroki Uchida, Yukio Iwashita, Masafumi Inomata

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


Background: Postoperative pancreatic fistula (POPF) is a major complication of distal pancreatectomy (DP). Several procedures for resection and closure of the pancreas have been proposed; however, the rate of POPF remains high. The aims of this study were to investigate the relationship between perioperative factors and POPF and to clarify the advantages of pre-firing compression of the pancreas in the DP. Patients and method: From 2008 to 2016, records of 75 patients who underwent DP were retrospectively reviewed. The relationship between the perioperative factors and clinically relevant POPF was investigated. Results: Univariate analysis showed that body mass index, thickness of the pancreas, and pre-firing compression were significantly related with clinically relevant POPF. Multivariate analysis showed that the pre-firing compression was an independent factor of clinically relevant POPF (OR = 44.31, 95%CI = 3.394–578.3, P = 0.004). Conclusions: Pre-firing compression of the pancreas can prevent clinically relevant POPF in DP.

Original languageEnglish
Pages (from-to)506-510
Number of pages5
JournalAmerican Journal of Surgery
Issue number3
Publication statusPublished - Sept 2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery


Dive into the research topics of 'Effect of pre-firing compression on the prevention of pancreatic fistula in distal pancreatectomy'. Together they form a unique fingerprint.

Cite this