Effect of hydrophilicity on the properties of a degradable polylactide

Yvonne Boxberg, Matthias Schnabelrauch, Sebastian Vogt, Manuel Salmerón Sánchez, Gloria Gallego Ferrer, Manuel Monleón Pradas, Julio Suay Antón

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


A series of polylactide networks has been prepared by the copolymerization of a biodegradable oligolactide macromer with hydrophobic methyl methacrylate monomer and hydrophilic hydroxyethyl acrylate monomer, with different amounts of the hydrophilic monomer. The incorporation of the hydrophilic units into the network has been characterized with thermogravimetric analysis, differential scanning calorimetry, and dynamic mechanical spectrometry. A homogeneous material results, showing a single glass-transition temperature and a characteristic relaxation behavior that is not the sum of those of the pure components separately. Additional hydrophilic units in the network chains lower the rubbery modulus, keeping a high modulus value at room temperature, and manifestly increase the degradation rate of the polymer. This can be attributed both to the higher water swellability of the network when hydrophilic units are present and to the higher water diffusion coefficient in a network, which has a lower crosslinking density.

Original languageEnglish
Pages (from-to)656-664
Number of pages9
JournalJournal of Polymer Science, Part B: Polymer Physics
Issue number4
Publication statusPublished - Feb 15 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry
  • Polymers and Plastics
  • Materials Chemistry


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