@article{e5a918e178e54e958dd7c629e2703190,
title = "Effect of DNA methylation on the velocity of DNA translocation through a nanochannel",
abstract = "Here, we report the effect of DNA methylation on the velocity of DNA translocation through a nanochannel, as determined by measuring differences in translocation velocities between methylated and non-methylated DNA molecules. We found that the velocity of translocation of methylated DNA was faster than that of non-methylated DNA, which we attributed to variation in the coefficients of diffusion and friction with the nanochannel wall, due to the increased molecular weight and stiffness, respectively, of methylated DNA.",
author = "Xiaoyin Sun and Takao Yasui and Takeshi Yanagida and Noritada Kaji and Sakon Rahong and Masaki Kanai and Kazuki Nagashima and Tomoji Kawai and Yoshinobu Baba",
note = "Funding Information: This research was supported by the Cabinet Office, Government of Japan and the Japan Society for the Promotion of Science (JSPS) through the Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program), the ImPACT Program of the Council for Science, Technology and Innovation (Cabinet Office, Government of Japan), the Nanotechnology Platform Program (Molecule and Material Synthesis) of the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan, the JSPS Grant-in-Aid for Scientific Research (A) 16H02091, and PRESTO, Japan Science and Technology Agency (JST). Publisher Copyright: {\textcopyright} 2017 The Japan Society for Analytical Chemistry.",
year = "2017",
doi = "10.2116/analsci.33.727",
language = "English",
volume = "33",
pages = "727--730",
journal = "analytical sciences",
issn = "0910-6340",
publisher = "The Japan Society for Analytical Chemistry",
number = "6",
}