TY - GEN
T1 - Effect of DBD plasma on human cells in presence of osmolytes and denaturant
AU - Kaushik, Nagendra Kumar
AU - Attri, Pankaj
AU - Choi, Eun Ha
AU - Kaushik, Neha
N1 - Funding Information:
The present Research has been conducted by the Research Grant of Kwangwoon University in 2012. The authors would also like to gratefully acknowledge financial support by SRC program of National Research Foundation of Korea (20100029418) in 2012.
Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012
Y1 - 2012
N2 - Non thermal plasma is emerging as a novel tool for the treatment of living tissues for biological and medical purpose. In this study we described the effect of DBD (dielectric barrier discharge) plasma on both cancer and normal cell line in presence of osmolytes. Osmolytes having unique protective metabolic roles and also found in animal body, they are acting as antioxidants, providing redox balance, detoxifying sulfide, protect macromolecules, enhance protein folding and regulate cell volume. Based on these interesting properties of osmolytes, non thermal plasma in presence of osmolytes appears to provide a new outlook. Results of this study reveals that osmolytes in presence of plasma act as protecting agent for normal cells however, not to cancer cells in the presence of plasma. The main goal of this study is to protect normal cells from the toxic effect of DBD plasma.
AB - Non thermal plasma is emerging as a novel tool for the treatment of living tissues for biological and medical purpose. In this study we described the effect of DBD (dielectric barrier discharge) plasma on both cancer and normal cell line in presence of osmolytes. Osmolytes having unique protective metabolic roles and also found in animal body, they are acting as antioxidants, providing redox balance, detoxifying sulfide, protect macromolecules, enhance protein folding and regulate cell volume. Based on these interesting properties of osmolytes, non thermal plasma in presence of osmolytes appears to provide a new outlook. Results of this study reveals that osmolytes in presence of plasma act as protecting agent for normal cells however, not to cancer cells in the presence of plasma. The main goal of this study is to protect normal cells from the toxic effect of DBD plasma.
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U2 - 10.1557/opl.2012.872
DO - 10.1557/opl.2012.872
M3 - Conference contribution
AN - SCOPUS:84879509691
SN - 9781627482622
T3 - Materials Research Society Symposium Proceedings
SP - 1
EP - 8
BT - Plasma Processing and Diagnostics for Life Sciences
T2 - 2012 MRS Spring Meeting
Y2 - 9 April 2012 through 13 April 2012
ER -
