Effect of channel geometry on ionic current signal of a bridge circuit based microfluidic channel

Hirotoshi Yasaki; Takao Yasui; Takeshi Yanagida; Noritada Kaji; Masaki Kanai; Kazuki Nagashima; Tomoji Kawai; Yoshinobu Baba

doi:10.1246/cl.171139

Effect of channel geometry on ionic current signal of a bridge circuit based microfluidic channel

Hirotoshi Yasaki, Takao Yasui, Takeshi Yanagida, Noritada Kaji, Masaki Kanai, Kazuki Nagashima, Tomoji Kawai, Yoshinobu Baba

Department of Integrated Materials

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Bridge circuit based ionic current sensing in a microfluidic channel has attracted attention as a highly sensitive analytical method for bio-related molecules and particles. However, channel geometry which greatly influences the detected ionic current has not been investigated. Here, we investigate experimentally and theoretically the effect of differences in the microfluidic channel geometry on shapes and amplitude of signals in ionic current sensing. Our results clarify the geometrical effect of the channel in the bridge circuit based ionic current sensing method.

Original language	English
Pages (from-to)	350-353
Number of pages	4
Journal	Chemistry Letters
Volume	47
Issue number	3
DOIs	https://doi.org/10.1246/cl.171139
Publication status	Published - 2018

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1246/cl.171139

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title = "Effect of channel geometry on ionic current signal of a bridge circuit based microfluidic channel",

abstract = "Bridge circuit based ionic current sensing in a microfluidic channel has attracted attention as a highly sensitive analytical method for bio-related molecules and particles. However, channel geometry which greatly influences the detected ionic current has not been investigated. Here, we investigate experimentally and theoretically the effect of differences in the microfluidic channel geometry on shapes and amplitude of signals in ionic current sensing. Our results clarify the geometrical effect of the channel in the bridge circuit based ionic current sensing method.",

author = "Hirotoshi Yasaki and Takao Yasui and Takeshi Yanagida and Noritada Kaji and Masaki Kanai and Kazuki Nagashima and Tomoji Kawai and Yoshinobu Baba",

note = "Funding Information: This research was supported by Grant-in-Aid for JSPS Research Fellow No. 15J03490, PREST (Nos. JPMJPR151B, JPMJPR16F4), JST, the JSPS Grant-in-Aid for Young Scientists (A) No. 17H04803, the ImPACT Program of the Council for Science, Technology and Innovation (Cabinet Office, Government of Japan), and the JSPS Grant-in-Aid for Scientific Research (A) No. 16H02091. Publisher Copyright: {\textcopyright} 2018 The Chemical Society of Japan.",

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doi = "10.1246/cl.171139",

language = "English",

volume = "47",

pages = "350--353",

journal = "Chemistry Letters",

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TY - JOUR

T1 - Effect of channel geometry on ionic current signal of a bridge circuit based microfluidic channel

AU - Yasaki, Hirotoshi

AU - Yasui, Takao

AU - Yanagida, Takeshi

AU - Kaji, Noritada

AU - Kanai, Masaki

AU - Nagashima, Kazuki

AU - Kawai, Tomoji

AU - Baba, Yoshinobu

N1 - Funding Information: This research was supported by Grant-in-Aid for JSPS Research Fellow No. 15J03490, PREST (Nos. JPMJPR151B, JPMJPR16F4), JST, the JSPS Grant-in-Aid for Young Scientists (A) No. 17H04803, the ImPACT Program of the Council for Science, Technology and Innovation (Cabinet Office, Government of Japan), and the JSPS Grant-in-Aid for Scientific Research (A) No. 16H02091. Publisher Copyright: © 2018 The Chemical Society of Japan.

PY - 2018

Y1 - 2018

N2 - Bridge circuit based ionic current sensing in a microfluidic channel has attracted attention as a highly sensitive analytical method for bio-related molecules and particles. However, channel geometry which greatly influences the detected ionic current has not been investigated. Here, we investigate experimentally and theoretically the effect of differences in the microfluidic channel geometry on shapes and amplitude of signals in ionic current sensing. Our results clarify the geometrical effect of the channel in the bridge circuit based ionic current sensing method.

AB - Bridge circuit based ionic current sensing in a microfluidic channel has attracted attention as a highly sensitive analytical method for bio-related molecules and particles. However, channel geometry which greatly influences the detected ionic current has not been investigated. Here, we investigate experimentally and theoretically the effect of differences in the microfluidic channel geometry on shapes and amplitude of signals in ionic current sensing. Our results clarify the geometrical effect of the channel in the bridge circuit based ionic current sensing method.

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DO - 10.1246/cl.171139

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VL - 47

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EP - 353

JO - Chemistry Letters

JF - Chemistry Letters

IS - 3

ER -

Effect of channel geometry on ionic current signal of a bridge circuit based microfluidic channel

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