TY - JOUR
T1 - Effect of age factors on health-related quality of life in patients with lower rectal cancer after sphincter-saving surgery
T2 - A 1-year longitudinal study
AU - Kinoshita, Yumiko
AU - Izukura, Rieko
AU - Miyazono, Mami
AU - Nagai, Shuntaro
AU - Oki, Eiji
AU - Kanaoka, Maki
AU - Nakao, Hisako
AU - Chishaki, Akiko
AU - Mibu, Ryuichi
N1 - Funding Information:
This work was supported by Japan Society for the Promotion of Science (JSPS) KAKENHI under Grant numbers 21592755 , 24593301 , and 15K11625 .
Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Purpose: To examine age-related factors influencing health-related quality of life (HR-QOL) among patients with lower rectal cancer during the 12-month period after sphincter-saving surgery (SSS). Material and methods: In this 1-year longitudinal study, 137 patients (120 patients completed, and 82 aged ≥60 years) answered the European Organization for Research and Treatment of Cancer questionnaire (EORTC-C30/CR38) assessing their HR-QOL and related factors during the 12 months after SSS. Results: No significant differences in HR-QOL were found before surgery. Only among those aged ≥60 years, global health status/QOL and cognitive functioning showed a significant decrease one month after surgery. At one month after SSS, the role functioning of groups <60 years old (which is negatively related to defecation problems, insomnia, and financial difficulties) was lower compared to those aged ≥60 years; and role functioning was significantly related to global health status/QOL. Six months after SSS, the global health status/QOL had recovered. In both groups, global health status/QOL was related to role and social functioning. Among participants aged <60 years, global health status/QOL was significantly related to emotional functioning, which is related to future perspective. Among participants aged ≥60 years only, global health status/QOL was significantly related to cognitive functioning; pain, financial difficulties, and defecation problems negatively influenced HR-QOL. Symptoms specific after SSS: defecation problems (in both group), micturition problems (only ≥60 years), and sexual problems (only<60 years) influenced HR-QOL. Conclusion: Health care providers should assess the influence of age-related factors during the early post-operative period after SSS to improve HR-QOL.
AB - Purpose: To examine age-related factors influencing health-related quality of life (HR-QOL) among patients with lower rectal cancer during the 12-month period after sphincter-saving surgery (SSS). Material and methods: In this 1-year longitudinal study, 137 patients (120 patients completed, and 82 aged ≥60 years) answered the European Organization for Research and Treatment of Cancer questionnaire (EORTC-C30/CR38) assessing their HR-QOL and related factors during the 12 months after SSS. Results: No significant differences in HR-QOL were found before surgery. Only among those aged ≥60 years, global health status/QOL and cognitive functioning showed a significant decrease one month after surgery. At one month after SSS, the role functioning of groups <60 years old (which is negatively related to defecation problems, insomnia, and financial difficulties) was lower compared to those aged ≥60 years; and role functioning was significantly related to global health status/QOL. Six months after SSS, the global health status/QOL had recovered. In both groups, global health status/QOL was related to role and social functioning. Among participants aged <60 years, global health status/QOL was significantly related to emotional functioning, which is related to future perspective. Among participants aged ≥60 years only, global health status/QOL was significantly related to cognitive functioning; pain, financial difficulties, and defecation problems negatively influenced HR-QOL. Symptoms specific after SSS: defecation problems (in both group), micturition problems (only ≥60 years), and sexual problems (only<60 years) influenced HR-QOL. Conclusion: Health care providers should assess the influence of age-related factors during the early post-operative period after SSS to improve HR-QOL.
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U2 - 10.1016/j.archger.2018.09.004
DO - 10.1016/j.archger.2018.09.004
M3 - Article
C2 - 30269003
AN - SCOPUS:85054024227
SN - 0167-4943
VL - 79
SP - 185
EP - 191
JO - Archives of Gerontology and Geriatrics
JF - Archives of Gerontology and Geriatrics
ER -
