Dynamic MRI of the gallbladder lesions: Differentiation of benign from malignant

Kengo Yoshimitsu, Hiroshi Honda, Kuniyuki Kaneko, Toshiro Kuroiwa, Hiroyuki Irie, Takashi Ueki, Kazuo Chijiiwa, Kenji Takenaka, Kouji Masuda

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    59 Citations (Scopus)


    Forty-nine pathologically proven gallbladder lesions were evaluated in 45 patients using dynamic MRI with a spoiled gradient pulse sequence (SPGR), to access the ability of this technique to differentiate benign from malignant gallbladder lesions. The studies were reviewed retrospectively. Signal intensity of the lesions were measured. Twenty-one malignant and 28 benign lesions were classified into three categories: polypoid, diffuse wall thickening, and exophytic. Early and delayed enhancement patterns were evaluated. For the polypoid masses, malignant lesions (n = 9) demonstrated early and prolonged enhancements, whereas benign lesions (n = 14) had early enhancement with subsequent washout (P < .05). For diffuse gallbladder wall thickening, malignant lesions (n = 6) demonstrated early and prolonged enhancement and benign lesions (n = 14) showed relatively slow, prolonged enhancement (P < .05). The exophytic masses (n = 6) all were malignant and demonstrated early and prolonged enhancement. Dynamic MRI can help differentiate benign from malignant gallbladder lesions.

    Original languageEnglish
    Pages (from-to)696-701
    Number of pages6
    JournalJournal of Magnetic Resonance Imaging
    Issue number4
    Publication statusPublished - Jul 1997

    All Science Journal Classification (ASJC) codes

    • Radiology Nuclear Medicine and imaging


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