Dynamic behavior of cyclic enzyme systems

Masahiro Okamoto, Katsuya Hayashi

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


The dynamic behavior of cyclic enzyme systems where two enzymes share a substrate or cofactor in a cyclic manner is investigated by computer simulation. The dynamic characteristics of cyclic enzyme systems display catastrophic behavior in response to specific changes in external input without assuming allosteric regulation.

Original languageEnglish
Pages (from-to)591-598
Number of pages8
JournalJournal of Theoretical Biology
Issue number4
Publication statusPublished - Oct 21 1983
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Modelling and Simulation
  • General Biochemistry,Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences
  • Applied Mathematics


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