TY - JOUR
T1 - Dorisenones, cytotoxic spongian diterpenoids, from the nudibranch Chromodoris obsoleta
AU - Miyamoto, Tomofumi
AU - Sakamoto, Kenichiro
AU - Arao, Kazuyoshi
AU - Komori, Tetsuya
AU - Higuchi, Ryuichi
AU - Sasaki, Takuma
N1 - Funding Information:
Acknowledgments. -We thank Dr. R. Isobc, Mr. Y. Tanaka and Miss Y. Soeda of the Faculty of Pharmaceutical Sciences for providing MS and NMR data. This work was supported in part by a Grant-in Aid for Cancer Research (No. 04151040) and Scientific Research (No. 06453217) from The Ministry of Education, Science and Culture, Japan.
PY - 1996/6/10
Y1 - 1996/6/10
N2 - Seven new cytotoxic spongian diterpenoids, dorisenones A (1), B (2), C (3), D (4), 7α-hydroxyspongian-16-one (5), 15α, 16α-diacetoxy-11, 12β- epoxyspongian (6) and 7α-acetoxydendrillol-3 (7) were isolated from a Japanese marine mollusk Chromodoris obsoleta (Chromodorididae), together with four known spongian diterpenoids. Their structures have been elucidated by spectroscopic evidence and single crystal X ray analysis.
AB - Seven new cytotoxic spongian diterpenoids, dorisenones A (1), B (2), C (3), D (4), 7α-hydroxyspongian-16-one (5), 15α, 16α-diacetoxy-11, 12β- epoxyspongian (6) and 7α-acetoxydendrillol-3 (7) were isolated from a Japanese marine mollusk Chromodoris obsoleta (Chromodorididae), together with four known spongian diterpenoids. Their structures have been elucidated by spectroscopic evidence and single crystal X ray analysis.
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U2 - 10.1016/0040-4020(96)00388-2
DO - 10.1016/0040-4020(96)00388-2
M3 - Article
AN - SCOPUS:0029888835
SN - 0040-4020
VL - 52
SP - 8187
EP - 8198
JO - Tetrahedron
JF - Tetrahedron
IS - 24
ER -
