TY - JOUR
T1 - Dominant factors affecting extraction behavior of amino compounds by a calix[6]arene carboxylic acid derivative
AU - Oshima, Tatsuya
AU - Inoue, Katsutoshi
AU - Uezu, Kazuya
AU - Goto, Masahiro
N1 - Funding Information:
We are grateful for a grand-in-aid for scientific research (no. 14350419) from the Ministry of Education, Science, Sports and Culture of Japan. T.O. was supported by research fellowships from the Japan Society for the Promotion of Science (JSPS) for young scientists.
PY - 2004/5/3
Y1 - 2004/5/3
N2 - A calix[6]arene carboxylic acid derivative was utilized as an extractant for various amino compounds including amino acids. The host compound exhibited a high extractability compared to that of commercially available extractants such as di(2-ethylhexyl)phosphoric acid (D2EHPA). The important factors for amino acid extraction were found to be its cyclic structure and its cavity size, the functional carboxylic groups, and the length of the alkyl chains. The hydrophobicity and the ionic property of guest molecules also affect the extraction efficiency. Calix[6]arene forms a stable complex with a guest molecule by entrapping it into the cavity. The molecular geometries of calixarene before and after extraction were also discussed using computational calculations with the PM3 type of semi-empirical method.
AB - A calix[6]arene carboxylic acid derivative was utilized as an extractant for various amino compounds including amino acids. The host compound exhibited a high extractability compared to that of commercially available extractants such as di(2-ethylhexyl)phosphoric acid (D2EHPA). The important factors for amino acid extraction were found to be its cyclic structure and its cavity size, the functional carboxylic groups, and the length of the alkyl chains. The hydrophobicity and the ionic property of guest molecules also affect the extraction efficiency. Calix[6]arene forms a stable complex with a guest molecule by entrapping it into the cavity. The molecular geometries of calixarene before and after extraction were also discussed using computational calculations with the PM3 type of semi-empirical method.
UR - http://www.scopus.com/inward/record.url?scp=1542613864&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1542613864&partnerID=8YFLogxK
U2 - 10.1016/j.aca.2003.10.086
DO - 10.1016/j.aca.2003.10.086
M3 - Article
AN - SCOPUS:1542613864
SN - 0003-2670
VL - 509
SP - 137
EP - 144
JO - Analytica Chimica Acta
JF - Analytica Chimica Acta
IS - 2
ER -