Diverse metabolites of coral reef organisms

Junichi Tanaka, Masayuki Kuniyoshi, Chiaki Tanaka, Hamad H. Issa, Walter Balansa, Masahito Otsuka, Wahome P. Githige, Tatsuo Higa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


A detailed mechanism for the spontaneous transformation of 2-chloro-1-hydroxy-octoda-3(8),5-dien-4-one, a metabolite of Portieria hornemanni, into 4,5-dimethylbenzo[b]-furan was presented. Five new terpenoids have been isolated from the red alga Laurencia luzonensis. Five species of sponges yielded various metabolites: furanosesterterpenes from Ircinia sp., scalarane derivatives from Phyllospongia sp., polyketides from Theonella cf. swinhoei, a polyacetylene from Callyspongia sp., and cyclic depsipeptides from Suberites japonicus. Other new metabolites were sponge-derived secomanoalide derivative and imidazole alkaloids from nudibranchs, briarane class diterpenes from octocorals, and cyclofarnesylated hydroquinones, floresolides A-C, from an ascidian, Aplidium sp. Many of these compounds showed cytotoxicity.

Original languageEnglish
Pages (from-to)83-89
Number of pages7
JournalPure and Applied Chemistry
Issue number1
Publication statusPublished - Jan 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering


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