TY - JOUR
T1 - Digital gene atlas of neonate common marmoset brain
AU - Shimogori, Tomomi
AU - Abe, Ayumi
AU - Go, Yasuhiro
AU - Hashikawa, Tsutomu
AU - Kishi, Noriyuki
AU - Kikuchi, Satomi S.
AU - Kita, Yoshiaki
AU - Niimi, Kimie
AU - Nishibe, Hirozumi
AU - Okuno, Misako
AU - Saga, Kanako
AU - Sakurai, Miyano
AU - Sato, Masae
AU - Serizawa, Tsuna
AU - Suzuki, Sachie
AU - Takahashi, Eiki
AU - Tanaka, Mami
AU - Tatsumoto, Shoji
AU - Toki, Mitsuhiro
AU - U, Mami
AU - Wang, Yan
AU - Windak, Karl J.
AU - Yamagishi, Haruhiko
AU - Yamashita, Keiko
AU - Yoda, Tomoko
AU - Yoshida, Aya C.
AU - Yoshida, Chihiro
AU - Yoshimoto, Takuro
AU - Okano, Hideyuki
N1 - Funding Information:
The database is supported by the BSI-NI (BSI-Neuroinformatics) project. We thank the Neuroinformatics Japan Center (NIJC) for database construction. This work is supported by the RIKEN Brain Science Institute (TS) and Funding Program for World-leading Innovative R&D on Science and Technology (TS and HO) and Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) from Japan Agency for Medical Research and Development (AMED) (TS, YG and HO).
Funding Information:
The database is supported by the BSI-NI(BSI-Neuroinformatics) project. We thank the Neuroinformatics Japan Center (NIJC) for database construction. This work is supported by the RIKEN Brain Science Institute (TS) and Funding Program for World-leading Innovative R&D on Science and Technology (TS and HO) and Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) from Japan Agency for Medical Research and Development (AMED) (TS, YG and HO).
Publisher Copyright:
© 2017 Elsevier Ireland Ltd and Japan Neuroscience Society
PY - 2018/3
Y1 - 2018/3
N2 - Interest in the common marmoset (Callithrix jacchus) as a primate model animal has grown recently, in part due to the successful demonstration of transgenic marmosets. However, there is some debate as to the suitability of marmosets, compared to more widely used animal models, such as the macaque monkey and mouse. Especially, the usage of marmoset for animal models of human cognition and mental disorders, is still yet to be fully explored. To examine the prospects of the marmoset model for neuroscience research, the Marmoset Gene Atlas (https://gene-atlas.bminds.brain.riken.jp/) provides a whole brain gene expression atlas in the common marmoset. We employ in situ hybridization (ISH) to systematically analyze gene expression in neonate marmoset brains, which allows us to compare expression with other model animals such as mouse. We anticipate that these data will provide sufficient information to develop tools that enable us to reveal marmoset brain structure, function, cellular and molecular organization for primate brain research.
AB - Interest in the common marmoset (Callithrix jacchus) as a primate model animal has grown recently, in part due to the successful demonstration of transgenic marmosets. However, there is some debate as to the suitability of marmosets, compared to more widely used animal models, such as the macaque monkey and mouse. Especially, the usage of marmoset for animal models of human cognition and mental disorders, is still yet to be fully explored. To examine the prospects of the marmoset model for neuroscience research, the Marmoset Gene Atlas (https://gene-atlas.bminds.brain.riken.jp/) provides a whole brain gene expression atlas in the common marmoset. We employ in situ hybridization (ISH) to systematically analyze gene expression in neonate marmoset brains, which allows us to compare expression with other model animals such as mouse. We anticipate that these data will provide sufficient information to develop tools that enable us to reveal marmoset brain structure, function, cellular and molecular organization for primate brain research.
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U2 - 10.1016/j.neures.2017.10.009
DO - 10.1016/j.neures.2017.10.009
M3 - Article
C2 - 29111135
AN - SCOPUS:85032904506
SN - 0168-0102
VL - 128
SP - 1
EP - 13
JO - Neuroscience Research
JF - Neuroscience Research
ER -