Differentiation of cavernous hemangioma from schwannoma of the orbit: A dynamic MRI study

Atsuo Tanaka, Futoshi Mihara, Takashi Yoshiura, Osamu Togao, Yasuo Kuwabara, Yoshihiro Natori, Tomio Sasaki, Hiroshi Honda

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54 Citations (Scopus)


OBJECTIVE. The purpose of this study was to determine the capability of dynamic contrast MRI to differentiate hemangioma from schwannoma of the orbit. MATERIALS AND METHODS. Sixteen patients (three males and 13 females; mean age, 39 ± 17.3 [SD] years; age range, 10-71 years) with unilateral orbital tumors, including eight cavernous hemangiomas and eight schwannomas, were examined. In addition to conventional MRI, we performed a dynamic contrast study (fast spin-echo sequence, 20-sec interval) after bolus administration of the contrast material (gadopentetate dimeglumine, 0.1 mmol/kg). We evaluated the features of the contrast enhancement spread pattern and the tumors' time-intensity curves. RESULTS. In the early phase, all the hemangiomas started the enhancement from one point or portion, although all the schwannomas started the enhancement from a wide area. The difference in the contrast-enhancement spread pattern features between the two types of tumors was statistically significant (p < 0.0001). The gradient of the time-intensity curve did not show a significant difference. CONCLUSION. Hemangioma and schwannoma of the orbit can be differentiated by the contrast-enhancement spread pattern on dynamic MRI.

Original languageEnglish
Pages (from-to)1799-1804
Number of pages6
JournalAmerican Journal of Roentgenology
Issue number6
Publication statusPublished - Dec 2004

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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