Different SPECT findings before and after Capgras' syndrome in interictal psychosis

Hideki Horikawa, Akira Monji, Masayuki Sasaki, Toshihiko Maekawa, Toshiaki Onitsuka, Yoko Nitazaka, Yoji Hirano, Shougo Hirano, Sadayuki Hashioka, Takahiro Kato, Ichiro Yoshida, Shigenobu Kanba

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


We herein report a case of Capgras' syndrome observed in interictal psychosis in which the single-photon emission computed tomography (SPECT) findings before and after the appearance of the psychotic symptoms differed. SPECT with 99mTc-hexamethyl propyleneamine oxine (HMPAO) revealed worsening of hypoperfusion in the entire right hemisphere after onset of the psychotic symptoms. The enhanced hypoperfusion demonstrated by SPECT in the present case seems to indicate a right interhemispheric disconnection resulting in the occurrence of Capgras' syndrome.

Original languageEnglish
Pages (from-to)189-192
Number of pages4
JournalEpilepsy and Behavior
Issue number1
Publication statusPublished - Aug 2006

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience


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