TY - JOUR
T1 - Differences between features of adenoma in the rectum versus sigmoid colon
AU - Ikeda, Yoichi
AU - Mori, Masaki
AU - Akagi, Kazunari
AU - Iwashita, Akinori
AU - Haraguchi, Yukiaki
AU - Maehara, Yoshihiko
AU - Sugimachi, Keizo
PY - 2000
Y1 - 2000
N2 - OBJECTIVE: Although the prevalence of cancer in the rectosigmoid is high compared with that in the more proximal colon, the features of cancer developing from an adenoma have yet to be eluciated. The aim of this study is to examine the clinicopathological relationship between cancer and adenoma in the rectosigmoid. METHODS: A total of 340 adenomas located in the rectosigmoid in 255 patients were retrospectively examined regarding such clinicopathological factors as location and the grade of dysplasia. RESULTS: The prevalence of adenoma was 102 in the rectum and 238 in the sigmoid colon, respectively, whereas the prevalence of adenoma with high-grade dysplasia was 39 in the rectum and 48 in the sigmoid colon, respectively. This prevalence of adenoma with high-grade dysplasia was thus significantly higher in the rectum than in the sigmoid colon (p < 0.02). CONCLUSIONS: These findings suggest the possibility of different types of cancer development between adenoma of the rectum and sigmoid colon. (C) 2000 by Am. Coll. of Gastroenterology.
AB - OBJECTIVE: Although the prevalence of cancer in the rectosigmoid is high compared with that in the more proximal colon, the features of cancer developing from an adenoma have yet to be eluciated. The aim of this study is to examine the clinicopathological relationship between cancer and adenoma in the rectosigmoid. METHODS: A total of 340 adenomas located in the rectosigmoid in 255 patients were retrospectively examined regarding such clinicopathological factors as location and the grade of dysplasia. RESULTS: The prevalence of adenoma was 102 in the rectum and 238 in the sigmoid colon, respectively, whereas the prevalence of adenoma with high-grade dysplasia was 39 in the rectum and 48 in the sigmoid colon, respectively. This prevalence of adenoma with high-grade dysplasia was thus significantly higher in the rectum than in the sigmoid colon (p < 0.02). CONCLUSIONS: These findings suggest the possibility of different types of cancer development between adenoma of the rectum and sigmoid colon. (C) 2000 by Am. Coll. of Gastroenterology.
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U2 - 10.1016/S0002-9270(00)02172-9
DO - 10.1016/S0002-9270(00)02172-9
M3 - Article
C2 - 11151902
AN - SCOPUS:0033634834
SN - 0002-9270
VL - 95
SP - 3620
EP - 3623
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 12
ER -
