Diethylenetriamine-Mediated Direct Cleavage of Unactivated Carbamates and Ureas

Megumi Noshita, Yuhei Shimizu, Hiroyuki Morimoto, Takashi Ohshima

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


Diethylenetriamine is effective for the direct cleavage of unactivated carbamates and ureas without additional reagents and catalysts. Various carbamates and ureas were cleaved to afford products in good yield, and the reactions were not affected by air or moisture. Unique chemoselective cleavage of carbamate and urea in the presence of amides was also achieved.

Original languageEnglish
Pages (from-to)6062-6065
Number of pages4
JournalOrganic letters
Issue number23
Publication statusPublished - Dec 2 2016

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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