Development of photoswitchable fluorescent molecules using arylazopyrazole

Kenji Torii, Yuichiro Hori, Keiichiro Watabe, Kazuya Kikuchi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Photoswitchable fluorescent molecules (PSFMs) are important tools for fluorescence imaging of biomolecules. To date, PSFMs have been applied for pulse-chase experiments and super-resolution imaging. However, most have limitations in that their fluorophores have low photostability or require cytotoxic additives. Here, we have developed PSFMs using a photochromic compound, arylazopyrazole, to overcome these limitations. These molecules showed reversible changes in fluorescence intensity upon photoirradiation and high photostability in aqueous solutions.

Original languageEnglish
Pages (from-to)821-824
Number of pages4
JournalBulletin of the Chemical Society of Japan
Issue number7
Publication statusPublished - Jul 2020
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry


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