Development of palm-sized differential plasmon resonance meter based on concept of Sprode

Akihide Hemmi; Toshihiko Imato; Yoshio Aoki; Masahiro Sato; Nobuaki Soh; Yasukazu Asano; Chika Akasaka; Saeko Okutani; Satoshi Ohkubo; Noriaki Kaneki; Koji Shimada; Tetsuya Eguchi; Toshiaki Oinuma

doi:10.1016/j.snb.2004.12.103

Development of palm-sized differential plasmon resonance meter based on concept of Sprode

Akihide Hemmi, Toshihiko Imato, Yoshio Aoki, Masahiro Sato, Nobuaki Soh, Yasukazu Asano, Chika Akasaka, Saeko Okutani, Satoshi Ohkubo, Noriaki Kaneki, Koji Shimada, Tetsuya Eguchi, Toshiaki Oinuma

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

A palm-sized differential surface plasmon resonance (SPR) meter, which consisted of a single light source, a prism, a divided mirror, and a single linear CCD element, was developed aiming at the miniaturization of an SPR instrument for use in field analysis of endocrine disrupting chemicals. The size and weight of the meter were 160 cm (W) × 10 cm (H) × 6 cm (D) and 770 g, respectively. The SPR meter composed of an Sprode with the sample and reference sensor-cells was found to be very effective for compensating drift and fluctuation of sensor signals as well as temperature variation at the same time without time lag. The effectiveness was due to a subtraction function of reference signal from the sample signal. The basic performance of the meter was a drift of within 0.001° in SPR measurement over 4300 s and a angle stability of within 0.0004° at a 10° incident LED light beam. Also, the SPR meter was applied to the immunoassay of 2,4-dichlorophenol (2,4-DCP) using a solid extraction technique. A good linear relationship between the concentration of 2,4-DCP and the SPR signal was obtained with the present meter. It was possible to determine 10 ppb of 2,4-DCP with the developed meter. A new concept of a divided mirror and the Sprode was thought to be useful for miniaturization of the SPR instrument aimed at on-site analysis.

Original language	English
Pages (from-to)	893-898
Number of pages	6
Journal	Sensors and Actuators, B: Chemical
Volume	108
Issue number	1-2 SPEC. ISS.
DOIs	https://doi.org/10.1016/j.snb.2004.12.103
Publication status	Published - Jul 22 2005

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Instrumentation
Condensed Matter Physics
Surfaces, Coatings and Films
Metals and Alloys
Electrical and Electronic Engineering
Materials Chemistry

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10.1016/j.snb.2004.12.103

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title = "Development of palm-sized differential plasmon resonance meter based on concept of Sprode",

abstract = "A palm-sized differential surface plasmon resonance (SPR) meter, which consisted of a single light source, a prism, a divided mirror, and a single linear CCD element, was developed aiming at the miniaturization of an SPR instrument for use in field analysis of endocrine disrupting chemicals. The size and weight of the meter were 160 cm (W) × 10 cm (H) × 6 cm (D) and 770 g, respectively. The SPR meter composed of an Sprode with the sample and reference sensor-cells was found to be very effective for compensating drift and fluctuation of sensor signals as well as temperature variation at the same time without time lag. The effectiveness was due to a subtraction function of reference signal from the sample signal. The basic performance of the meter was a drift of within 0.001° in SPR measurement over 4300 s and a angle stability of within 0.0004° at a 10° incident LED light beam. Also, the SPR meter was applied to the immunoassay of 2,4-dichlorophenol (2,4-DCP) using a solid extraction technique. A good linear relationship between the concentration of 2,4-DCP and the SPR signal was obtained with the present meter. It was possible to determine 10 ppb of 2,4-DCP with the developed meter. A new concept of a divided mirror and the Sprode was thought to be useful for miniaturization of the SPR instrument aimed at on-site analysis.",

author = "Akihide Hemmi and Toshihiko Imato and Yoshio Aoki and Masahiro Sato and Nobuaki Soh and Yasukazu Asano and Chika Akasaka and Saeko Okutani and Satoshi Ohkubo and Noriaki Kaneki and Koji Shimada and Tetsuya Eguchi and Toshiaki Oinuma",

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T1 - Development of palm-sized differential plasmon resonance meter based on concept of Sprode

AU - Hemmi, Akihide

AU - Imato, Toshihiko

AU - Aoki, Yoshio

AU - Sato, Masahiro

AU - Soh, Nobuaki

AU - Asano, Yasukazu

AU - Akasaka, Chika

AU - Okutani, Saeko

AU - Ohkubo, Satoshi

AU - Kaneki, Noriaki

AU - Shimada, Koji

AU - Eguchi, Tetsuya

AU - Oinuma, Toshiaki

PY - 2005/7/22

Y1 - 2005/7/22

N2 - A palm-sized differential surface plasmon resonance (SPR) meter, which consisted of a single light source, a prism, a divided mirror, and a single linear CCD element, was developed aiming at the miniaturization of an SPR instrument for use in field analysis of endocrine disrupting chemicals. The size and weight of the meter were 160 cm (W) × 10 cm (H) × 6 cm (D) and 770 g, respectively. The SPR meter composed of an Sprode with the sample and reference sensor-cells was found to be very effective for compensating drift and fluctuation of sensor signals as well as temperature variation at the same time without time lag. The effectiveness was due to a subtraction function of reference signal from the sample signal. The basic performance of the meter was a drift of within 0.001° in SPR measurement over 4300 s and a angle stability of within 0.0004° at a 10° incident LED light beam. Also, the SPR meter was applied to the immunoassay of 2,4-dichlorophenol (2,4-DCP) using a solid extraction technique. A good linear relationship between the concentration of 2,4-DCP and the SPR signal was obtained with the present meter. It was possible to determine 10 ppb of 2,4-DCP with the developed meter. A new concept of a divided mirror and the Sprode was thought to be useful for miniaturization of the SPR instrument aimed at on-site analysis.

AB - A palm-sized differential surface plasmon resonance (SPR) meter, which consisted of a single light source, a prism, a divided mirror, and a single linear CCD element, was developed aiming at the miniaturization of an SPR instrument for use in field analysis of endocrine disrupting chemicals. The size and weight of the meter were 160 cm (W) × 10 cm (H) × 6 cm (D) and 770 g, respectively. The SPR meter composed of an Sprode with the sample and reference sensor-cells was found to be very effective for compensating drift and fluctuation of sensor signals as well as temperature variation at the same time without time lag. The effectiveness was due to a subtraction function of reference signal from the sample signal. The basic performance of the meter was a drift of within 0.001° in SPR measurement over 4300 s and a angle stability of within 0.0004° at a 10° incident LED light beam. Also, the SPR meter was applied to the immunoassay of 2,4-dichlorophenol (2,4-DCP) using a solid extraction technique. A good linear relationship between the concentration of 2,4-DCP and the SPR signal was obtained with the present meter. It was possible to determine 10 ppb of 2,4-DCP with the developed meter. A new concept of a divided mirror and the Sprode was thought to be useful for miniaturization of the SPR instrument aimed at on-site analysis.

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IS - 1-2 SPEC. ISS.

ER -

Development of palm-sized differential plasmon resonance meter based on concept of Sprode

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