Development of individual fitness score for conformity of prescriptions to the “Guidelines For Pharmacological Therapy of Schizophrenia”

Ken Inada, Kentaro Fukumoto, Naomi Hasegawa, Yuka Yasuda, Hisashi Yamada, Hikaru Hori, Kayo Ichihashi, Hitoshi Iida, Kazutaka Ohi, Hiroyuki Muraoka, Fumitoshi Kodaka, Kenta Ide, Naoki Hashimoto, Jun ichi Iga, Kazuyoshi Ogasawara, Kiyokazu Atake, Yoshikazu Takaesu, Tatsuya Nagasawa, Hiroshi Komatsu, Tsuyoshi OkadaRyuji Furihata, Mikio Kido, Saya Kikuchi, Chika Kubota, Manabu Makinodan, Shinichiro Ochi, Masahiro Takeshima, Hirotaka Yamagata, Junya Matsumoto, Kenichiro Miura, Masahide Usami, Taishiro Kishimoto, Toshiaki Onitsuka, Eiichi Katsumoto, Akitoyo Hishimoto, Shusuke Numata, Norio Yasui-Furukori, Koichiro Watanabe, Ryota Hashimoto

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Aims: The Guidelines for the Pharmacotherapy of Schizophrenia were established to improve the quality of medical care, and the EGUIDE project was conducted to train clinicians on guideline usage. A quality indicator (QI) was established to measure the prevalence of the guidelines, and a survey was conducted, which revealed a gap between the guidelines and actual clinical practice (evidence-practice-gap). The purpose of this study was to develop an individual fitness score (IFS) formula that expresses the degree to which prescribers adhere to the Guidelines for Pharmacological Therapy of Schizophrenia in a simple manner, and to determine the validity of this formula from a survey of the prescriptions of the EGUIDE project participants'. Methods: To establish appropriate scores, members discussed the proposed formula and then voted on them. The IFS formula developed was set up so that antipsychotic monotherapy would be given 100 points, with points deducted if concomitant or adjunctive antipsychotic medications were used, and a minimum score of 0. To validate this formula, prescriptions of hospitalized schizophrenic patients at admission and at discharge were scored and compared. Result: IFS points vary and ranged from 0 to100. The average pre-admission score for all subjects was 45.6, and the average score at discharge was 54, those were significantly higher during discharge. Conclusions: We developed an IFS formula, a tool to easily visualize the degree to which current prescriptions conform to the guidelines for the pharmacological treatment of schizophrenia.

Original languageEnglish
Pages (from-to)502-509
Number of pages8
JournalNeuropsychopharmacology Reports
Volume42
Issue number4
DOIs
Publication statusPublished - Dec 2022

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)

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