DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES

Kazuya Fujita; Niko Kimura; Toyohiro Naito; Noritada Kaji

DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES

Kazuya Fujita, Niko Kimura, Toyohiro Naito, Noritada Kaji

Functional Materials Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this study, we have developed a microfluidic electroporation system for seamless production of exosomal nanomedicines. The developed microfluidic device composed of a complete micro-mixing region and a micro-electroporation region allowed effective production of doxorubicin hydrochloride (DOX)-loaded exosomes with high DOX loading efficiency. The developed integrated micro-electroporation system is expected to contribute to optimization of production conditions for preparation of various anticancer drugs and nucleic acids-loaded exosomal nanomedicines.

Original language	English
Title of host publication	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	659-660
Number of pages	2
ISBN (Electronic)	9781733419031
Publication status	Published - 2021
Event	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States Duration: Oct 10 2021 → Oct 14 2021

Publication series

Name	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/Territory	United States
City	Palm Springs, Virtual
Period	10/10/21 → 10/14/21

All Science Journal Classification (ASJC) codes

Bioengineering
Chemical Engineering (miscellaneous)

Cite this

Fujita, K., Kimura, N., Naito, T., & Kaji, N. (2021). DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 659-660). (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.

DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES. / Fujita, Kazuya; Kimura, Niko; Naito, Toyohiro et al.
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. p. 659-660 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fujita, K, Kimura, N, Naito, T & Kaji, N 2021, DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES. in MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 659-660, 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021, Palm Springs, Virtual, United States, 10/10/21.

Fujita K, Kimura N, Naito T, Kaji N. DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2021. p. 659-660. (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Fujita, Kazuya ; Kimura, Niko ; Naito, Toyohiro et al. / DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. pp. 659-660 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

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ER -

DEVELOPMENT OF A MICRO-ELECTROPORATION SYSTEM FOR HIGH THROUGHPUT PRODUCTION OF ANTICANCER DRUG-LOADED EXOSOMAL NANOMEDICINES

Abstract

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Conference

All Science Journal Classification (ASJC) codes

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