TY - JOUR
T1 - Development of a computer-aided diagnosis system for continuous peritoneal dialysis
T2 - An availability of the simultaneous numerical optimization technique for kinetic parameters in the peritoneal dialysis model
AU - Hamada, Hiroyuki
AU - Namoto, Shinji
AU - Yamada, Ryo
AU - Al Mamun, Abdullah
AU - Yamashita, Akihiro C.
AU - Ishizaki, Makoto
AU - Okamoto, Masahiro
N1 - Funding Information:
This study was supported by the Grants-in-Aid for Scientific Research (Japanese Society for the Promotion of Science) No. 15790431 and 18790568.
PY - 2007/12
Y1 - 2007/12
N2 - We developed a novel diagnostic system for continuous peritoneal dialysis, which evaluates the peritoneal permeability and hydraulic conductance (peritoneal function) by applying the kinetic model and a clinical test with minimum nursing time. Kinetic parameters for the peritoneal function were determined by the simultaneous numerical optimization techniques (SNOT). Furthermore dialysis outcome and ultrafiltration volume were estimated and predicted by using the kinetic model with a set of optimal kinetic parameters, which were in agreement with measured data (r2 > 0.82). The clinical implementation of the SNOT is very useful to explore the better prescriptions for each patient's clinical condition.
AB - We developed a novel diagnostic system for continuous peritoneal dialysis, which evaluates the peritoneal permeability and hydraulic conductance (peritoneal function) by applying the kinetic model and a clinical test with minimum nursing time. Kinetic parameters for the peritoneal function were determined by the simultaneous numerical optimization techniques (SNOT). Furthermore dialysis outcome and ultrafiltration volume were estimated and predicted by using the kinetic model with a set of optimal kinetic parameters, which were in agreement with measured data (r2 > 0.82). The clinical implementation of the SNOT is very useful to explore the better prescriptions for each patient's clinical condition.
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U2 - 10.1016/j.compbiomed.2007.04.004
DO - 10.1016/j.compbiomed.2007.04.004
M3 - Article
C2 - 17548068
AN - SCOPUS:35348851950
SN - 0010-4825
VL - 37
SP - 1700
EP - 1708
JO - Computers in Biology and Medicine
JF - Computers in Biology and Medicine
IS - 12
ER -