Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT: Comparison with histologic findings

Akihiro Nishie; Kengo Yoshimitsu; Yoshiki Asayama; Hiroyuki Irie; Hitoshi Aibe; Tsuyoshi Tajima; Kenji Shinozaki; Tomohiro Nakayama; Daisuke Kakihara; Mitsuo Shimada; Shin Ichi Aishima; Kisaku Yoshida; Hiroshi Honda

doi:10.2214/ajr.184.4.01841157

Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT: Comparison with histologic findings

Akihiro Nishie, Kengo Yoshimitsu, Yoshiki Asayama, Hiroyuki Irie, Hitoshi Aibe, Tsuyoshi Tajima, Kenji Shinozaki, Tomohiro Nakayama, Daisuke Kakihara, Mitsuo Shimada, Shin Ichi Aishima, Kisaku Yoshida, Hiroshi Honda

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68 Citations (Scopus)

Abstract

OBJECTIVE. The purpose of this study was to evaluate the performance of enhanced CT in making a diagnosis of combined hepatocellular and cholangiocarcinomas (HCC-CCs) by comparing CT findings with histologic findings. CONCLUSION. One third (nine of 27 cases) of the combined HCC-CCs were correctly diagnosed on enhanced CT by detailed analysis of the enhancing pattern around or within the mass. Various factors such as an atypical enhancing pattern, the size of each component, and the presence of a mass composed of intermediate tumor cells-that is, cells with intermediate characteristics between HCC and CC-were found to be the causes of misdiagnosis of combined HCC-CC on enhanced CT.

Original language	English
Pages (from-to)	1157-1162
Number of pages	6
Journal	American Journal of Roentgenology
Volume	184
Issue number	4
DOIs	https://doi.org/10.2214/ajr.184.4.01841157
Publication status	Published - 2005

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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Nishie, A., Yoshimitsu, K., Asayama, Y., Irie, H., Aibe, H., Tajima, T., Shinozaki, K., Nakayama, T., Kakihara, D., Shimada, M., Aishima, S. I., Yoshida, K., & Honda, H. (2005). Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT: Comparison with histologic findings. American Journal of Roentgenology, 184(4), 1157-1162. https://doi.org/10.2214/ajr.184.4.01841157

Nishie, A, Yoshimitsu, K, Asayama, Y, Irie, H, Aibe, H, Tajima, T, Shinozaki, K, Nakayama, T, Kakihara, D, Shimada, M, Aishima, SI, Yoshida, K & Honda, H 2005, 'Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT: Comparison with histologic findings', American Journal of Roentgenology, vol. 184, no. 4, pp. 1157-1162. https://doi.org/10.2214/ajr.184.4.01841157

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abstract = "OBJECTIVE. The purpose of this study was to evaluate the performance of enhanced CT in making a diagnosis of combined hepatocellular and cholangiocarcinomas (HCC-CCs) by comparing CT findings with histologic findings. CONCLUSION. One third (nine of 27 cases) of the combined HCC-CCs were correctly diagnosed on enhanced CT by detailed analysis of the enhancing pattern around or within the mass. Various factors such as an atypical enhancing pattern, the size of each component, and the presence of a mass composed of intermediate tumor cells-that is, cells with intermediate characteristics between HCC and CC-were found to be the causes of misdiagnosis of combined HCC-CC on enhanced CT.",

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T1 - Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT

T2 - Comparison with histologic findings

AU - Nishie, Akihiro

AU - Yoshimitsu, Kengo

AU - Asayama, Yoshiki

AU - Irie, Hiroyuki

AU - Aibe, Hitoshi

AU - Tajima, Tsuyoshi

AU - Shinozaki, Kenji

AU - Nakayama, Tomohiro

AU - Kakihara, Daisuke

AU - Shimada, Mitsuo

AU - Aishima, Shin Ichi

AU - Yoshida, Kisaku

AU - Honda, Hiroshi

PY - 2005

Y1 - 2005

N2 - OBJECTIVE. The purpose of this study was to evaluate the performance of enhanced CT in making a diagnosis of combined hepatocellular and cholangiocarcinomas (HCC-CCs) by comparing CT findings with histologic findings. CONCLUSION. One third (nine of 27 cases) of the combined HCC-CCs were correctly diagnosed on enhanced CT by detailed analysis of the enhancing pattern around or within the mass. Various factors such as an atypical enhancing pattern, the size of each component, and the presence of a mass composed of intermediate tumor cells-that is, cells with intermediate characteristics between HCC and CC-were found to be the causes of misdiagnosis of combined HCC-CC on enhanced CT.

AB - OBJECTIVE. The purpose of this study was to evaluate the performance of enhanced CT in making a diagnosis of combined hepatocellular and cholangiocarcinomas (HCC-CCs) by comparing CT findings with histologic findings. CONCLUSION. One third (nine of 27 cases) of the combined HCC-CCs were correctly diagnosed on enhanced CT by detailed analysis of the enhancing pattern around or within the mass. Various factors such as an atypical enhancing pattern, the size of each component, and the presence of a mass composed of intermediate tumor cells-that is, cells with intermediate characteristics between HCC and CC-were found to be the causes of misdiagnosis of combined HCC-CC on enhanced CT.

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Detection of combined hepatocellular and cholangiocarcinomas on enhanced CT: Comparison with histologic findings

Abstract

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