Detection of axillary node metastasis using diffusion-weighted MRI in breast cancer

Takeshi Kamitani; Masamitsu Hatakenaka; Hidetake Yabuuchi; Yoshio Matsuo; Nobuhiro Fujita; Mikako Jinnouchi; Michinobu Nagao; Kengo Shirahane; Eriko Tokunaga; Hiroshi Honda

doi:10.1016/j.clinimag.2012.02.014

Detection of axillary node metastasis using diffusion-weighted MRI in breast cancer

Takeshi Kamitani, Masamitsu Hatakenaka, Hidetake Yabuuchi, Yoshio Matsuo, Nobuhiro Fujita, Mikako Jinnouchi, Michinobu Nagao, Kengo Shirahane, Eriko Tokunaga, Hiroshi Honda

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Breast magnetic resonance imagings (MRIs) including diffusion-weighted MRI (DWI) of 110 breast cancers (26 with pathologically proven axillary node metastasis and 84 without metastasis) were retrospectively studied. Axillary nodes were detected as high-signal-intensity areas on DWI in 71 cancers (24 with metastasis and 47 without) and not detected in 39 cancers (2 with metastasis and 37 without). The ADC of metastatic nodes was significantly greater than that of the benign ones (1.08±0.18×10^-3 mm²/s vs. 0.92±0.22×10^-3 mm²/s, P=004). When detectability of axillary nodes on DWI and ADC over 1.05×10^-3 mm²/s was applied as a threshold, 53.8% sensitivity, 86.9% specificity, and 79.1% accuracy were provided.

Original language	English
Pages (from-to)	56-61
Number of pages	6
Journal	Clinical Imaging
Volume	37
Issue number	1
DOIs	https://doi.org/10.1016/j.clinimag.2012.02.014
Publication status	Published - Jan 2013

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.clinimag.2012.02.014

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title = "Detection of axillary node metastasis using diffusion-weighted MRI in breast cancer",

abstract = "Breast magnetic resonance imagings (MRIs) including diffusion-weighted MRI (DWI) of 110 breast cancers (26 with pathologically proven axillary node metastasis and 84 without metastasis) were retrospectively studied. Axillary nodes were detected as high-signal-intensity areas on DWI in 71 cancers (24 with metastasis and 47 without) and not detected in 39 cancers (2 with metastasis and 37 without). The ADC of metastatic nodes was significantly greater than that of the benign ones (1.08±0.18×10-3 mm2/s vs. 0.92±0.22×10-3 mm2/s, P=004). When detectability of axillary nodes on DWI and ADC over 1.05×10-3 mm2/s was applied as a threshold, 53.8% sensitivity, 86.9% specificity, and 79.1% accuracy were provided.",

author = "Takeshi Kamitani and Masamitsu Hatakenaka and Hidetake Yabuuchi and Yoshio Matsuo and Nobuhiro Fujita and Mikako Jinnouchi and Michinobu Nagao and Kengo Shirahane and Eriko Tokunaga and Hiroshi Honda",

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doi = "10.1016/j.clinimag.2012.02.014",

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T1 - Detection of axillary node metastasis using diffusion-weighted MRI in breast cancer

AU - Kamitani, Takeshi

AU - Hatakenaka, Masamitsu

AU - Yabuuchi, Hidetake

AU - Matsuo, Yoshio

AU - Fujita, Nobuhiro

AU - Jinnouchi, Mikako

AU - Nagao, Michinobu

AU - Shirahane, Kengo

AU - Tokunaga, Eriko

AU - Honda, Hiroshi

PY - 2013/1

Y1 - 2013/1

N2 - Breast magnetic resonance imagings (MRIs) including diffusion-weighted MRI (DWI) of 110 breast cancers (26 with pathologically proven axillary node metastasis and 84 without metastasis) were retrospectively studied. Axillary nodes were detected as high-signal-intensity areas on DWI in 71 cancers (24 with metastasis and 47 without) and not detected in 39 cancers (2 with metastasis and 37 without). The ADC of metastatic nodes was significantly greater than that of the benign ones (1.08±0.18×10-3 mm2/s vs. 0.92±0.22×10-3 mm2/s, P=004). When detectability of axillary nodes on DWI and ADC over 1.05×10-3 mm2/s was applied as a threshold, 53.8% sensitivity, 86.9% specificity, and 79.1% accuracy were provided.

AB - Breast magnetic resonance imagings (MRIs) including diffusion-weighted MRI (DWI) of 110 breast cancers (26 with pathologically proven axillary node metastasis and 84 without metastasis) were retrospectively studied. Axillary nodes were detected as high-signal-intensity areas on DWI in 71 cancers (24 with metastasis and 47 without) and not detected in 39 cancers (2 with metastasis and 37 without). The ADC of metastatic nodes was significantly greater than that of the benign ones (1.08±0.18×10-3 mm2/s vs. 0.92±0.22×10-3 mm2/s, P=004). When detectability of axillary nodes on DWI and ADC over 1.05×10-3 mm2/s was applied as a threshold, 53.8% sensitivity, 86.9% specificity, and 79.1% accuracy were provided.

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Detection of axillary node metastasis using diffusion-weighted MRI in breast cancer

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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